The TLS Foundation is involved in numerous PNRR (National Recovery and Resilience Plan) and PNC (National Plan for Complementary Investments) projects, which are key opportunities for the life sciences ecosystem development. More specifically, TLS is involved in promoting and strengthening the cooperation between the research field, the productive system, and the regional and national institutions. The main projects in which the TLS Foundation is involved are:

Tuscany Health Ecosystem (THE)

The Tuscany Health Ecosystem (THE) is one of the 11 nationally funded innovation ecosystems, but, differently from the others, is entirely dedicated to life sciences. The main goal of the project is to stimulate and support the growth and the consolidation of the life sciences ecosystem in Tuscany through a multidisciplinary approach, specialized skills, cross-contamination of technology and knowledge, and efficient communication between researchers, clinicians, and companies. The THE aims to respond to the needs of the life sciences field in terms of innovation and education, thus allowing for the consolidation of the regional ecosystem and its competitiveness on a regional, national, and global level. The subjects of interest of the Tuscany Health Ecosystem are advanced radiotherapies and diagnostics in oncology, preventive and predictive medicine, state-of-the-art technologies, methods, and materials for human health and wellbeing, nanotechnologies for diagnostics and therapies, innovation for health and wellbeing, precision medicine and personalized healthcare, innovation in translational medicine, biotechnologies and imaging in neurosciences, robotics and automation, and people’s wellness. The TLS Foundation supports the Ecosystem in technology transfer activities, business start-up activities, regulatory support, dissemination and partnering.

HEAL Italia

HEAL ItaliaHealth Extended ALliance for Innovative Therapies, Advanced Lab-research, and Integrated Approaches of Precision Medicine is the first national chain focused on research and innovation in precision medicine. The TLS Foundation is involved as one of the 24 partners from 11 different Italian regions. The project is part of one of the 14 extended partnerships envisioned by “Dalla Ricerca all’Impresa”, 2nd component of the 4th mission of the NRPP, with the aim of investing in innovation clusters to strengthen the research sector on a national scale and promote their involvement in European and global value chains. The HEAL ITALIA project, which has a budget of 114.7 million euros, has been proposed by the University of Palermo (as leading proponent) and other 11 Universities, 5 Scientific Institutes for Research, Hospitalisation and Health Care, 6 companies, one research foundation and the University of Pittsburgh Medical Center. Scientists, technologists and young researchers aim at sharing and developing knowledge, studies and innovative technologies through a holistic and multidisciplinary approach in order to bring state-of-the-art Precision Medicine into the Italian Health Service thanks to innovative methods, innovative services and, above all, a valuable network of clinical data in support of translational research for advanced diagnostics and therapies in the fight against cancer and cardiovascular, metabolic and rare diseases.

Life Science TTO Network: PerfeTTO

The Life Science TTO Network project, funded under the “Ecosistemi innovativi della salute – Rete di centri di trasferimento tecnologico” program (complementary fundings), led by the Centro Cardiologico Monzino IRCCS, aims at creating and consolidating a network of technology transfer centers in order to strengthen the Italian Health Service. The project will last 42 months, and the TLS Foundation is involved as 2nd level Spoke, member of the Project Committee and, through the UVaR office (Ufficio per la Valorizzazione della Ricerca, lit. office for the enhancement of research), supporter of the participation of Territorial Technical Offices, institutions pertaining to the Regional Health Service and Tuscany’s Universities in the project. Funds receives: 15 million euros (100K for TLS Foundation).

The Life Science TTO NETWORK, named “PerfeTTO”, sees the involvement of I and II level Spoke located throughout Italy. Its aim is to promote technology transfer activities and the creation of new innovative start-ups and spin-offs in the life sciences sector. Existing technology transfer facilities such as Technology Transfer Offices (TTOs) of Universities and Public Research Institutions, facilities operating in several Institutes for Treatment and Research and other NHS entities, regional TTOs, and networks of TT Offices will be pooled and systematised, integrating and providing technical support. 54 associates, including Institutes for Treatment and Research, universities, public and private bodies, all organized into Level I and Level II HUBs and Spokes, are participating in the project. The Centro Cardiologico Monzino in Milan, the Istituto Romagnolo per lo Studio dei Tumori “Dino Amadori” and the Institute for Treatment and Research “Saverio de Bellis” will represent the whole national network. The aim of the project is to build an innovative health ecosystem through the creation of clinical-translational research networks of excellence within the National Health Service, capable of pooling available technologies and existing expertise. The project will last 8 years, and it will be cofunded by the Italian Ministry of Health for 4 years.

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ALISEI (Advanced Life Science in Italy) is the National Technology Cluster for Life Sciences, which aims to promote interaction between the research system, the entrepreneurial and productive fabric and public institutions in the healthcare sector, a strategic research and innovation nexus for Italy.

CSA Projects

In its role as facilitator of an innovation ecosystem, the TLS Foundation is increasingly positioning itself as a system aggregator and facilitator in the life sciences, both at the territorial level and on international projects.


TLS works to foster dialogue and partnerships between public and private entities. It has created and continues to implement collaboration networks in the field of life sciences with the aim of offering incubated companies access to contacts and opportunities.