Emanuele Roscioli

Emanuele Roscioli received his Ph.D. in Genetics and Molecular Biology in at Sapienza, University of Rome, Italy. His main expertise is the study of biological processes through high resolution and high content microscopy approaches. These include fixed- and live-cell based assays and micromanipulation/microinjection of cells. Throughout his research career, Emanuele acquired competence in microbiology, cell biology, molecular biology, biophysics and biochemistry. He worked on interdisciplinary projects alongside physicists and mathematical modelers to develop image analysis tools.
Currently, Emanuele is a Research Scientist at Fondazione Toscana Life Sciences working on the discovery and functional characterization of monoclonal antibodies (mAbs) against antimicrobial resistant bacteria and tumorigenic markers on cancer cells. Emanuele previously worked as Research Fellow at the Centre for Mechanochemical Cell Biology, University of Warwick, Coventry, UK, studying how changes in the kinetochore architecture modulate chromosome segregation in human cells. He used cell-based assays and computational approaches to investigate how different kinetochore components responded to stabilisation of microtubule-exerted forces and to loss of microtubule attachment during mitosis. Before, he was a Postdoctoral Associate at Virginia Bioinformatic Institute, Virginia Tech, Blacksburg, VA, USA where he combined cell biology and biophysical approaches to investigate the mechanical properties of the kinetochore in live cells. As PhD student, Emanuele worked at the Institute of Molecular Biology and Pathology, CNR, Rome – Sapienza, University of Rome, Italy, researching the role of GTPase Ran in modulating chromosome segregation, microtubule dynamics, and kinetochore function in human cells.