Il sempre maggiore impegno di TLS anche sul fronte della ricerca propria, ha visto negli ultimi anni una notevole crescita del contributo scientifico dei ricercatori e delle ricercatrici della Fondazione, con pubblicazioni presenti sulle principali riviste scientifiche internazionali come The Lancet, Nature, Cell, Current Opinion in Immunology, Frontiers in Oncology, PNAS.
PUBBLICAZIONI SCIENTIFICHE
| Autori | Titolo | Testata | DOI |
|---|---|---|---|
| D’Errico G, Duda-Sikula M, Zwiefka A, Krzyzanowski D, Kurpas D. | Health technologies and smart & integrated care–key action 2 stage of the Regions4PerMed (H2020) project | Medical Science Pulse. 2019;13(4) | Link |
| Moramarco F, Pezzicoli A, Salvini L, Leuzzi R, Pansegrau W, Balducci E. | A LONELY GUY protein of Bordetella pertussis with unique features is related to oxidative stress | Scientific reports. 2019 Nov 19;9(1):1-2 | Link |
| Tagliabue A, Leite LC, Leroy OY, Rappuoli R. | A global perspective on vaccines: priorities, challenges and online information | Frontiers in immunology. 2019 Nov 12;10:2556. | Link |
| Paolino M, Visintin M, Margotti E, Visentini M, Salvini L, Reale A, Razzano V, Giuliani G, Caselli G, Tavanti F, Menziani MC, Cappelli A. | Functionalization of protein hexahistidine tags by functional nanoreactors | New Journal of Chemistry. 2019;43(46):17946-53 | Link |
| Irene C, Fantappiè L, Caproni E, Zerbini F, Anesi A, Tomasi M, Zanella I, Stupia S, Prete S, Valensin S, König E, Frattini L, Gagliardi A, Isaac SJ, Grandi A, Guella G, Grandi G. | Bacterial outer membrane vesicles engineered with lipidated antigens as a platform for Staphylococcus aureus vaccine | Proceedings of the National Academy of Sciences. 2019 Oct 22;116(43):21780-8 | Link |
| Zurli V, Montecchi T, Heilig R, Poschke I, Volkmar M, Wimmer G, Boncompagni G, Turacchio G, D’Elios MM, Campoccia G, Resta N, Offringa R, Fischer R, Acuto O, Baldari CT, Kabanova A. | Phosphoproteomics of CD2 signaling reveals an AMPK-dependent regulation of lytic granule polarization in cytotoxic T cells | bioRxiv. 2019 Jan 1:795963 | Link |
| D’Errico G, Cormio PG, Bello P, Duda-Sikuła M, Zwiefka A, Krzyżanowski, EA Stegemann, BA Requeijo, JM Romero Fidalgo, D Kurpas. | Interregional coordination for a fast and deep uptake of personalised health (Regions4Permed) –multidisciplinary consortium under the H2020 project | Medical Science Pulse 2019 (13) 3© Copyright by PMWSZ w Opolu. 2019 Jul 1;13:60. | Link |
| Paolino M, Reale A, Razzano V, Giuliani G, Donati A, Giorgi G, Boccia AC, Mendichi R, Piovani D, Botta C, Salvini L, Samperi F, Savoca C, Licciardi M, Paccagnini E, Gentile M, Cappelli A. | Physicochemical properties of a new pegylated polybenzofulvene brush for drug encapsulation | Pharmaceutics. 2019 Sep;11(9):444. | Link |
| Cicaloni V, Spiga O, Dimitri GM, Maiocchi R, Millucci L, Giustarini D, Bernardini G, Bernini A, Marzocchi B, Braconi D, Santucci A. | Interactive alkaptonuria database: investigating clinical data to improve patient care in a rare disease | The FASEB Journal. 2019 Nov;33(11):12696-703 | Link |
| Andreano E, Seubert A, Rappuoli R. | Human monoclonal antibodies for discovery, therapy, and vaccine acceleration | Current opinion in immunology. 2019 Aug 1;59:130-4 | Link |
| Seib KL, Haag AF, Oriente F, Fantappiè L, Borghi S, Semchenko EA, Schulz BL, Ferlicca F, Taddei AR, Giuliani MM, Pizza M, Delany I. | The meningococcal vaccine antigen GNA2091 is an analogue of YraP and plays key roles in outer membrane stability and virulence | The FASEB Journal. 2019 Nov;33(11):12324-35 | Link |
| Andreano E, D'Oro U, Rappuoli R, Finco O. | Vaccine evolution and its application to fight modern threats | Frontiers in immunology. 2019 Jul 25;10:1722 | Link |
| Gerna G, Kabanova A, Lilleri D. | Human cytomegalovirus cell tropism and host cell receptors | Vaccines. 2019 Sep;7(3):70 | Link |
| Paolino M, Reale A, Razzano V, Giuliani G, Donati A, Bonechi C, Caselli G, Visintin M, Makovec F, Scialabba C, Licciardi M, Paccagnini E, Gentile M, Salvini L, Tavanti F, Menziani MC, Cappelli A. | Nanoreactors for the multi-functionalization of poly-histidine fragments | New Journal of Chemistry. 2019;43(18):6834-7 | Link |
| Ascher DB, Spiga O, Sekelska M, Pires DE, Bernini A, Tiezzi M, Kralovicova J, Borovska I, Soltysova A, Olsson B, Galderisi S, Cicaloni V, Ranganath L, Santucci A, Zatkova A. | Homogentisate 1, 2-dioxygenase (HGD) gene variants, their analysis and genotype–phenotype correlations in the largest cohort of patients with AKU | European Journal of Human Genetics. 2019 Jun;27(6):888-902 | Link |
| Autori | Titolo | Testata | DOI |
|---|---|---|---|
| Andreano E, Piccini G, Licastro D, Casalino L, Johnson NV, Paciello I, Dal Monego S, Pantano E, Manganaro N, Manenti A, Manna R, Casa E, Hyseni I, Benincasa L, Montomoli E, Amaro RE, McLellan JS, Rappuoli R. | SARS-CoV-2 escape in vitro from a highly neutralizing COVID-19 convalescent plasma | BioRxiv. 2020 Jan 1 | Link |
| Kabanova A, Gavriilaki E, Pelzer BW, Brunetti L, Maiques-Diaz A. | Effect of the COVID-19 pandemic on laboratory and clinical research: a testimony and a call to action from researchers | HemaSphere. 2020 Dec;4(6) | Link |
| Ristori E, Cicaloni V, Salvini L, Tinti L, Tinti C, Simons M, Corti F, Donnini S, Ziche M. | Amyloid-β Precursor Protein APP Down-Regulation Alters Actin Cytoskeleton-Interacting Proteins in Endothelial Cells | Cells. 2020 Nov;9(11):2506 | Link |
| Borges NM, Kabanova A, Scherer F. | Change is Coming: Plan S From the Early Career Scientist Perspective | HemaSphere. 2020 Dec;4(6) | Link |
| Ciabattini A, Garagnani P, Santoro F, Rappuoli R, Franceschi C, Medaglini D. | Shelter from the cytokine storm: Pitfalls and prospects in the development of SARS-CoV-2 vaccines for an elderly population | InSeminars in immunopathology 2020 Nov 6 (pp. 1-16). Springer Berlin Heidelberg | Link |
| Cicaloni V, Pecorelli A, Cordone V, Tinti L, Rossi M, Hayek J, Salvini L, Tinti C, Valacchi G. | A proteomics approach to further highlight the altered inflammatory condition in Rett syndrome | Archives of Biochemistry and Biophysics. 2020 Dec 15; 696:108660 | Link |
| Schneikart G, Tavarini S, Sammicheli C, Torricelli G, Guidotti S, Andreano E, Buricchi F, D'Oro U, Finco O, Bardelli M | The respiratory syncytial virus fusion protein-specific B cell receptor repertoire reshaped by post-fusion subunit vaccination | Vaccine. 2020 Nov 25;38(50):7916-27. | Link |
| Troisi M, Andreano E, Sala C, Kabanova A, Rappuoli R. | Vaccines as remedy for antimicrobial resistance and emerging infections | Current Opinion in Immunology. 2020 Aug 1; 65:102-6 | Link |
| Sala C, Benjak A, Goletti D, Banu S, Mazza-Stadler J, Jaton K, Busso P, Remm S, Leleu M, Rougemont J, Palmieri F, Cuzzi G, Butera O, Vanini V, Kabir S, Rahman SMM, Nicod L, Cole ST. | Multicenter analysis of sputum microbiota in tuberculosis patients | PloS one. 2020 Oct 12;15(10):e0240250 | Link |
| Andreano E, Nicastri E, Paciello I, Pileri P, Manganaro N, Piccini G, Manenti A, Pantano E, Kabanova A, Troisi M, Vacca F, Cardamone D, De Santi C, Benincasa L, Agrati C, Capobianchi MR, Castilletti C, Emiliozzi A, Fabbiani M, Montagnani F, Depau L, Brunetti J, Bracci L, Montomoli E, Sala C, Ippolito G, Rappuoli R. | Extremely potent human monoclonal antibodies from convalescent Covid-19 patients | bioRxiv. 2020 Jan 1 | Link |
| Bucci E, Andreev K, Björkman A, Calogero RA, Carafoli E, Carninci P, Castagnoli P, Cossarizza A, Mussini C, Guerin P, Lipworth B, Sbardella G, Stocki T, Tuosto L, van Tulleken C, Viola A. | Safety and efficacy of the Russian COVID-19 vaccine: more information needed | The Lancet. 2020 Oct 3;396(10256):e53 | Link |
| Sala C, Chiarelli LR, Riccardi G. | Editorial on Special Issue “Tuberculosis Drug Discovery and Development 2019” | Applied Sciences. 2020;10(17):6069 | Link |
| Ricciardi-Castagnoli P. | Sensing the gut microbiota | Nature Immunology. 2020 Jul;21(7):704-5 | Link |
| Rossi A, Giacomini G, Cicaloni V, Galderisi S, Milella MS, Bernini A, Millucci L, Spiga O, Bianchini M, Santucci A. | AKUImg: A database of cartilage images of Alkaptonuria patients | Computers in Biology and Medicine. 2020 Jul 1; 122:103863 | Link |
| Maio M, Hamid O, Larkin J, Covre A, Altomonte M, Calabrò L, Vardhana SA, Robert C, Ibrahim R, Anichini A, Wolchok JD, Giacomo AMD. | Immune checkpoint inhibitors for cancer therapy in the COVID-19 era | Clinical Cancer Research. 2020 Aug 15;26(16):4201-5 | Link |
| Rappuoli R. | Drugs and Vaccines Will Be Necessary to Control Tuberculosis | Applied Sciences. 2020;10(11):4026 | Link |
| Rosini R, Nicchi S, Pizza M, Rappuoli R. | Vaccines against antimicrobial resistance. | Frontiers in immunology. 2020 Jun 3;11:1048. | Link |
| Montico B, Colizzi F, Giurato G, Rizzo A, Salvati A, Baboci L, Benedetti D, Pivetta E, Covre A, Dal Bo M, Weisz A, Steffan A, Maio M, Sigalotti L, Fratta E. | Loss of Spry1 reduces growth of BRAF V600-mutant cutaneous melanoma and improves response to targeted therapy | Cell death & disease. 2020 May 22;11(5):1-5 | Link |
| Cicaloni V, Pecorelli A, Tinti L, Rossi M, Benedusi M, Cervellati C, Spiga O, Santucci A, Hayek J, Salvini L, Tinti C, Valacchi G. | Proteomic profiling reveals mitochondrial alterations in Rett syndrome | Free Radical Biology and Medicine. 2020 Aug 1; 155:37-48 | Link |
| Andreano E, Nicastri E, Paciello I, Pileri P, Manganaro N, Piccini G, Manenti A, Pantano E, Kabanova A, Troisi M, Vacca F, Cardamone D, De Santi C, Agrati C, Capobianchi MR, Castilletti C, Emiliozzi A, Fabbiani M, Montagnani F, Montomoli E, Sala C, Ippolito G, Rappuoli R. | Identification of neutralizing human monoclonal antibodies from Italian Covid-19 convalescent patients | bioRxiv. 2020 Jan 1 | Link |
| Medaglini D, Andersen P, Rappuoli R. | Advanced Immunization Technologies for Next Generation Vaccines | Frontiers in Immunology. 2020 May 6;11:878 | Link |
| Pieterman ED, Sarink MJ, Sala C, Cole ST, de Steenwinkel JE, Bax HI. | Advanced quantification methods to improve the 18b dormancy model for assessing the activity of tuberculosis drugs in vitro | Antimicrobial agents and chemotherapy. 2020 Apr 27;64(7): e00280-20 | Link |
| Gries R, Sala C, Rybniker J. | Host-directed therapies and anti-virulence compounds to address anti-microbial resistant tuberculosis infection | Applied Sciences. 2020 Jan;10(8):2688. | Link |
| Spiga O, Cicaloni V, Fiorini C, Trezza A, Visibelli A, Millucci L, Bernardini G, Bernini A, Marzocchi B, Braconi D, Prischi F, Santucci A. | Machine learning application for development of a data-driven predictive model able to investigate quality of life scores in a rare disease | Orphanet journal of rare diseases 2020 Dec;15(1):1-0 | Link |
| Milazzo FM, Vesci L, Anastasi AM, Chiapparino C, Rosi A, Giannini G, Taddei M, Cini E, Faltoni V, Petricci E, Battistuzzi G, Salvini L, Carollo V, De Santis R. | ErbB2 targeted epigenetic modulation: anti-tumor efficacy of the ADC trastuzumab-HDACi ST8176AA1 | Frontiers in oncology. 2020 Jan 23; 9:1534 | Link |
| Aarestrup FM, Albeyatti A, Armitage WJ, Auffray C, Augello L, Balling R, Benhabiles N, Bertolini G, Bjaalie JG, Black M, Blomberg N, Bogaert P, Bubak M, Claerhout B, Clarke L, De Meulder B, D'Errico G, Di Meglio A, Forgo N, Gans-Combe C, Gray AE, Gut I, Gyllenberg A, Hemmrich-Stanisak G, Hjorth L, Ioannidis Y, Jarmalaite S, Kel A, Kherif F, Korbel JO, Larue C, Laszlo M, Maas A, Magalhaes L, Manneh-Vangramberen I, Morley-Fletcher E, Ohmann C, Oksvold P, Oxtoby NP, Perseil I, Pezoulas V, Riess O, Riper H, Roca J, Rosenstiel P, Sabatier P, Sanz F, Tayeb M, Thomassen G, Van Bussel J, Van den Bulcke M, Van Oyen H. | Towards a European health research and innovation cloud (HRIC) | Genome medicine. 2020 Dec;12(1):1-4 | Link |
| Autori | Titolo | Testata | DOI |
|---|---|---|---|
| Andreano E, Paciello I, Piccini G, Manganaro N, Pileri P, Hyseni I, Leonardi M, Pantano E, Abbiento V, Benincasa L, Giglioli G, De Santi C, Fabbiani M, Rancan I, Tumbarello M, Montagnani F, Sala C, Montomoli E, Rappuoli R. | Hybrid immunity improves B cells and antibodies against SARS-CoV-2 variants. | Nature. 2021 Dec;600(7889):530-535. | Link |
| Vanni F, Lopresti L, Zurli V, Kabanova A, Cattaneo F, Sicuranza A, Gozzetti A, Gemma S, Zisterer DM, Bocchia M, Campiani G, Baldari CT, Butini S, Ulivieri C. | A novel class of oxazepine-based anti-cancer agents induces cell death in primary human CLL cells and efficiently reduces tumor growth in Eμ-TCL1 mice through the JNK/STAT4/p66Shc axis. | Pharmacol Res. 2021 Dec; 174:105965. | Link |
| Tomasi M, Dalsass M, Beghini F, Zanella I, Caproni E, Fantappiè L, Gagliardi A, Irene C, König E, Frattini L, Masetti G, Isaac SJ, Armanini F, Cumbo F, Blanco-Míguez A, Grandi A, Segata N, Grandi G. | Commensal Bifidobacterium Strains Enhance the Efficacy of Neo-Epitope Based Cancer Vaccines. | Vaccines (Basel). 2021 Nov 18;9(11):1356. | Link |
| König E, Gagliardi A, Riedmiller I, Andretta C, Tomasi M, Irene C, Frattini L, Zanella I, Berti F, Grandi A, Caproni E, Fantappiè L, Grandi G. | Multi-Antigen Outer Membrane Vesicle Engineering to Develop Polyvalent Vaccines: The Staphylococcus aureus Case. | Front Immunol. 2021 Nov 8;12:752168. | Link |
| Andreano E, Piccini G, Licastro D, Casalino L, Johnson NV, Paciello I, Dal Monego S, Pantano E, Manganaro N, Manenti A, Manna R, Casa E, Hyseni I, Benincasa L, Montomoli E, Amaro RE, McLellan JS, Rappuoli R. | SARS-CoV-2 escape from a highly neutralizing COVID-19 convalescent plasma | Proceedings of the National Academy of Sciences. 2021 Sep 7;118(36) | Link |
| Andreano E, Paciello I, Piccini G, Manganaro N, Pileri P, Hyseni I, Leonardi M, Pantano E, Abbiento V, Benincasa L, Giglioli G, De Santi C, Fabbiani M, Rancan I, Tumbarello M, Montagnani F, Sala C, Montomoli E, Rappuoli R. | Hybrid immunity improves B cell frequency, antibody potency and breadth against SARS-CoV-2 and variants of concern | bioRxiv. 2021 Jan 1 | Link |
| Lanini S, Milleri S, Andreano E, Nosari S, Paciello I, Piccini G, Gentili A, Phogat A, Hyseni I, Leonardi M, Torelli A, Montomoli E, Paolini A, Frosini A, Antinori A, Nicastri E, Girardi E, Plazzi MM, Ippolito G, Vaia F, Della Cioppa G, Rappuoli R. | A single intramuscular injection of monoclonal antibody MAD0004J08 induces in healthy adults SARS-CoV-2 neutralising antibody titres exceeding those induced by infection and vaccination | medRxiv. 2021 Jan 1 | Link |
| Pagano C, Baiocchi C, Beccari T, Blasi F, Cossignani L, Ceccarini MR, Orabona C, Orecchini E, Di Raimo E, Primavilla S, Salvini L, Di Michele A, Perioli L, Ricci M. | Emulgel Loaded with Flaxseed Extracts as New Therapeutic Approach in Wound Treatment | Pharmaceutics. 2021 Aug;13(8):1107 | Link |
| Stravalaci M, Pagani I, Paraboschi EM, Pedotti M, Doni A, Scavello F, Mapelli SN, Sironi M, Varani L, Matkovic M, Cavalli A, Cesana D, Gallina P, Pedemonte N, Capurro V, Clementi N, Mancini N, Invernizzi P, Rappuoli R, Duga S, Bottazzi B, Uguccioni M, Asselta R, Vicenzi E, Mantovani A, Garlanda C. | Recognition and inhibition of SARS-CoV-2 by humoral innate immunity pattern recognition molecules | medRxiv. 2021 Jan 1 | Link |
| Minenkova O, Santapaola D, Milazzo FM, Anastasi AM, Battistuzzi G, Chiapparino C, Rosi A, Gritti G, Borleri G, Rambaldi A, Dental C, Viollet C, Pagano B, Salvini L, Marra E , Luberto L, Rossi A, Riccio A, Merlo Pich E, Santoro MG and De Santis R, | Human single-chain antibodies neutralize SARS-CoV-2 variants by engaging an essential epitope of the spike: a new weapon against COVID-19 | bioRxiv 2021.06.04.447066; | Link |
| Romagnuolo I, Mariut C, Mazzoni A, Santis GD, Moltzen E, Ballensiefen W, Lange C, Frosini A, D’Errico G. | Sino-European science and technology collaboration on personalized medicine: overview, trends and future perspectives | Personalized Medicine. vol. 18, no. 5, pp. 455–470, 2021. | Link |
| Pettini F, Visibelli A, Cicaloni V, Iovinelli D, Spiga O. | Multi-Omics Model Applied to Cancer Genetics | International Journal of Molecular Sciences. 2021 Jan;22(11):5751 | Link |
| Andreano E, Rappuoli R. | SARS-CoV-2 escaped natural immunity, raising questions about vaccines and therapies | Nature Medicine. 2021 May;27(5):759-61 | Link |
| Nardini C, Osmani V, Cormio PG, Frosini A, Turrini M, Lionis C, Neumuth T, Ballensiefen W, Borgonovi E, D’Errico G. | The evolution of personalized healthcare and the pivotal role of European regions in its implementation | Personalized Medicine. 2021 May;18(3):283-94. | Link |
| Andreano E, Rappuoli R. | Immunodominant antibody germlines in COVID-19. | J Exp Med. 2021 May 3;218(5):e20210281. | Link |
| Andreano E, Nicastri E, Paciello I, Pileri P, Manganaro N, Piccini G, Manenti A, Pantano E, Kabanova A, Troisi M, Vacca F, Cardamone D, De Santi C, Torres JL, Ozorowski G, Benincasa L, Jang H, Di Genova C, Depau L, Brunetti J, Agrati C, Capobianchi MR, Castilletti C, Emiliozzi A, Fabbiani M, Montagnani F, Bracci L, Sautto G, Ross TM, Montomoli M, Temperton N, Ward AB, Sala C, Ippolito G, Rappuoli R. | Extremely potent human monoclonal antibodies from COVID-19 convalescent patients | Cell. 2021 Apr 1;184(7):1821-35.e16. | Link |
| Zanella I, König E, Tomasi M, Gagliardi A, Frattini L, Fantappiè L, Irene C, Zerbini F, Caproni E, Isaac SJ, Grigolato M, Corbellari R, Valensin S, Ferlenghi I, Giusti F, Bini L, Ashhab Y, Grandi A, Grandi G. | Proteome‐minimized outer membrane vesicles from Escherichia coli as a generalized vaccine platform | Journal of extracellular vesicles. 2021 Feb;10(4):e12066 | Link |
| Spiga O, Cicaloni V, Dimitri GM, Pettini F, Braconi D, Bernini A, Santucci A. | Machine learning application for patient stratification and phenotype/genotype investigation in a rare disease. | Briefings in Bioinformatics. 2021 Sep;22(5):bbaa434. | Link |
| Braconi D, Cicaloni V, Spiga O, Santucci A. | Personalized nutrition and omics technologies: current status and perspectives | Food Technology Disruptions. 2021 Jan 1:37-71 | Link |
| Pecetta S, Pizza M, Sala C, Andreano E, Pileri P, Troisi M, Pantano E, Manganaro N, Rappuoli R. | Antibodies, epicenter of SARS-CoV-2 immunology | Cell Death & Differentiation. 2021 Feb;28(2):821-824 | Link |
| Spiga O, Cicaloni V, Visibelli A, Davoli A, Paparo MA, Orlandini M, Vecchi B, Santucci A. | Towards a precision medicine approach based on machine learning for tailoring medical treatment in alkaptonuria | International journal of molecular sciences. 2021 Jan;22(3):1187 | Link |
| Galderisi S, Cicaloni V, Milella MS, Millucci L, Geminiani M, Salvini L, Tinti L, Tinti C, Vieira OV, Alves LS, Crevenna AH, Spiga O, Santucci A. | Homogentisic acid induces cytoskeleton and extracellular matrix alteration in alkaptonuric cartilage | Journal of Cellular Physiology. 2021 Aug;236(8):6011-24 | Link |
| Cianferotti C, Faltoni V, Cini E, Ermini E, Migliorini F, Petricci E, Taddei M, Salvini L, Battistuzzi G, Milazzo FM, Anastasi AM, Chiapparino C, De Santis R, Giannini G. | Antibody drug conjugates with hydroxamic acid cargos for histone deacetylase (HDAC) inhibition | Chemical Communications. 2021;57(7):867-70 | Link |
| Grieco G, Brusco N, Nigi L, Formichi C, Fignani D, Licata G, Marselli L, Marchetti P, Salvini L, Tinti L, Po A, Ferretti E, Sebastiani G, Dotta F. | Reduced miR-184-3p expression occurring in Type 2 diabetic pancreatic islets protects β-cells from lipotoxic and proinflammatory apoptosis via a CRTC1-dependent mechanism | bioRxiv 2021.01.04.425234; | Link |
| Karmakar M, Cicaloni V, Rodrigues CH, Spiga O, Santucci A, Ascher DB. | HGDiscovery: an online tool providing functional and phenotypic information on novel variants of homogentisate 1, 2-dioxigenase. | bioRxiv. 2021 Jan 1. | Link |
| Jonathan L. Torres, Gabriel Ozorowski, Emanuele Andreano, Hejun Liu, Jeffrey Copps, Giulia Piccini, Lorena Donnici, Matteo Conti, Cyril Planchais, Delphine Planas, Noemi Manganaro, Elisa Pantano, Ida Paciello, Piero Pileri, Timothée Bruel, Emanuele Montomoli, Hugo Mouquet, Olivier Schwartz, Claudia Sala, Raffaele De Francesco, Ian Wilson, Rino Rappuoli, Andrew B. Ward. | Structural insights of a highly potent pan-neutralizing SARS-CoV-2 human monoclonal antibody | bioRxiv. 2021 Oct 9. | Link |
| Selvaggio G, Leonardelli L, Lofano G, Fresnay S, Parolo S, Medini D, Siena E, Marchetti L. | A quantitative systems pharmacology approach to support mRNA vaccine development and optimization. | CPT Pharmacometrics Syst Pharmacol. 2021 Dec;10(12):1448-1451. | Link |
| Leonardelli L, Lofano G, Selvaggio G, Parolo S, Giampiccolo S, Tomasoni D, Domenici E, Priami C, Song H, Medini D, Marchetti L, Siena E. | Literature Mining and Mechanistic Graphical Modelling to Improve mRNA Vaccine Platforms. | Front Immunol. 2021 Sep 7;12:738388. | Link |
| Calabrò L, Rossi G, Morra A, Rosati C, Cutaia O, Daffinà MG, Altomonte M, Di Giacomo AM, Casula M, Fazio C, Palmieri G, Giannarelli D, Covre A, Maio M. | Tremelimumab plus durvalumab retreatment and 4-year outcomes in patients with mesothelioma: a follow-up of the open label, non-randomised, phase 2 NIBIT- MESO-1 study. | Lancet Respir Med. 2021 Sep;9(9):969-976. | Link |
| Sonia Budroni, Francesca Buricchi, AndreaCavallone, Gianfranco Volpini, Alessandra Mariani, Paola Lo Surdo, Christoph J.Blohmke, Giuseppe Del Giudice, Duccio Medini, Oretta Finco | Computational modeling of microfluidic data provides high-throughput affinity estimates for monoclonal antibodies | Computational and Structural Biotechnology Journal, Volume 19, 2021, Pages 3664-3672 | Link |
| Pecorelli A, Cordone V, Schiavone ML, Caffarelli C, Cervellati C, Cerbone G, Gonnelli S, Hayek J, Valacchi G. | Altered Bone Status in Rett Syndrome. | Life (Basel). 2021 Jun 3;11(6):521. | Link |
| Crivellari I, Pecorelli A, Cordone V, Marchi S, Pinton P, Hayek J, Cervellati C, Valacchi G. | Impaired mitochondrial quality control in Rett Syndrome. | Arch Biochem Biophys. 2021 Mar 30;700:108790. | Link |
| Alessio Mascolini, Dario Cardamone, Francesco Ponzio, Santa Di Cataldo, Elisa Ficarra | Exploiting generative self-supervised learning for the assessment of biological images with lack of annotations: a COVID-19 case-study | arXiv | Link |
| Autori | Titolo | Testata | DOI |
|---|---|---|---|
| Troisi M, Marini E, Abbiento V, Stazzoni S, Andreano E, Rappuoli R. | A new dawn for monoclonal antibodies against antimicrobial resistant bacteria. | Frontiers in Microbiology 2022;13. 14 December 2022 | Link |
| Benelli R, Costa D, Salvini L, Tardito S, Tosetti F, Villa F, Zocchi MR, Poggi A. | Targeting of colorectal cancer organoids with zoledronic acid conjugated to the anti-EGFR antibody cetuximab. | Journal for ImmunoTherapy of Cancer. 2022 Dec 1;10(12): e005660. | Link |
| Barbera S, Raucci L, Tassone G, Tinti L, Prischi F, Santucci A, Mongiat M, Tosi GM, Galvagni F, Dimberg A, Pozzi C. | Dimerization of the C-type lectin-like receptor CD93 promotes its binding to Multimerin-2 in endothelial cells. | International Journal of Biological Macromolecules.2022 Oct 18. | Link |
| Laghezza Masci V, Bernini R, Villanova N, Clemente M, Cicaloni V, Tinti L, Salvini L, Taddei AR, Tiezzi A, Ovidi E. | In Vitro Anti-Proliferative and Apoptotic Effects of Hydroxytyrosyl Oleate on SH-SY5Y Human Neuroblastoma Cells. | International Journal of Molecular Sciences.2022 Oct 15;23(20):12348. | Link |
| Muzzi A; Bodini M; Topaz N, Masignani V, Vadivelu K, Marjuki H, Wang X, Serino L, Medini. | Genetic Features of a Representative Panel of 110 Meningococcal B Isolates to Assess the Efficacy of Meningococcal B Vaccines | Msphere,7,5,e00385-22,2022, | Link |
| Vacca F, Sala C, Rappuoli R. | Monoclonal antibodies for bacterial pathogens: Mechanisms of action and engineering approaches for enhanced effector functions. | Biomedicines.2022 Aug 30;10(9):2126. | Link |
| Nezi P, Cicaloni V, Tinti L, Salvini L, Iannone M, Vitalini S, Garzoli S | Metabolomic and Proteomic Profile of Dried Hop Inflorescences (Humulus lupulus L. cv. Chinook and cv. Cascade) by SPME-GC-MS and UPLC-MS-MS. | Separations.2022 Aug 6;9(8):204. | Link |
| Mokhtary P, Pourhashem Z, Mehrizi AA, Sala C, Rappuoli R. | Recent Progress in the Discovery and Development of Monoclonal Antibodies against Viral Infections. | Biomedicines.2022 Aug 2;10(8):1861. | Link |
| Nardi F, Pezzella L, Drago R, Di Rita A, Simoncelli M, Marotta G, Gozzetti A, Bocchia M, Kabanova A. | Assessing gene function in human B cells: CRISPR/Cas9-based gene editing and mRNA-based gene expression in healthy and tumor cells. | European Journal of Immunology.2022 Aug. | Link |
| Andreano E, Paciello I, Pierleoni G, Maccari G, Antonelli G, Abbiento V, Pileri P, Benincasa L, Giglioli G, Piccini G, De Santi C. | mRNA vaccines and hybrid immunity use different B cell germlines to neutralize Omicron BA.4 and BA.5 | bioRxiv.2022:2022-08. | Link |
| Grieco GE, Brusco N, Fignani D, Nigi L, Formichi C, Licata G, Marselli L, Marchetti P, Salvini L, Tinti L, Po A. | Reduced miR-184-3p expression protects pancreatic β-cells from lipotoxic and proinflammatory apoptosis in type 2 diabetes via CRTC1 upregulation. | Cell death discovery.2022 Jul 29;8(1):1-3. | Link |
| Tomasi M, Caproni E, Benedet M, Zanella I, Giorgetta S, Dalsass M, K├Ânig E, Gagliardi A, Fantappi├¿ L, Berti A, Tamburini S, Croia L, Di Lascio G, Bellini E, Valensin S, Licata G, Sebastiani G, Dotta F, Armanini F, Cumbo F, Asnicar F, Blanco-M├¡guez A, Ruggiero E, Segata N, Grandi G, Grandi A. | Outer Membrane Vesicles From The Gut Microbiome Contribute to Tumor Immunity by Eliciting Cross-Reactive T Cells. | Front Oncol.2022 Jun 30;12:912639. | Link |
| Cicaloni V, Karmakar M, Frusciante L, Pettini F, Visibelli A, Orlandini M, Galvagni F, Mongiat M, Silk M, Nardi F, Ascher D. | Bioinformatic approaches to predict mutation effects in the binding site of the proangiogenic molecule CD93. | Frontiers in Bioinformatics.:54.21 June 2022. | Link |
| Cicaloni V, Costanti F, Pasqui A, Bianchini M, Niccolai N, Bongini P. | A Bioinformatics approach to investigate structural and non-structural proteins in human coronaviruses. | Frontiers in genetics. 2022 Jun 14:1303. | Link |
| Andreano E, Paciello I, Marchese S, Donnici L, Pierleoni G, Piccini G, Manganaro N, Pantano E, Abbiento V, Pileri P, Benincasa L. | Anatomy of Omicron BA. 1 and BA. 2 neutralizing antibodies in COVID-19 mRNA vaccinees. | Nature Communications. 2022 Jun 13;13(1):3375. | Link |
| Torres JL, Ozorowski G, Andreano E, Liu H, Copps J, Piccini G, Donnici L, Conti M, Planchais C, Planas D, Manganaro N. | Structural insights of a highly potent pan-neutralizing SARS-CoV-2 human monoclonal antibody. | Proceedings of the National Academy of Sciences. 2022 May 17;119(20): e2120976119. | Link |
| Minenkova O, Santapaola D, Milazzo FM, Anastasi AM, Battistuzzi G, Chiapparino C, Rosi A, Gritti G, Borleri G, Rambaldi A, Dental C, Viollet C, Pagano B, Salvini L, Marra E, Luberto L, Rossi A, Riccio A, Merlo Pich E, Santoro M G, De Santis R | Human inhalable antibody fragments neutralizing SARS-CoV-2 variants for COVID-19 therapy. | Molecular Therapy. 2022 May 4;30(5):1979-93. | Link |
| Prunas O, Weinberger D M, Medini D, Tizzoni M, Argante L | Evaluating the impact of meningococcal vaccines with synthetic controls | American Journal of Epidemiology,191,4,724-734,2022,Oxford University Press. April 2022 | Link |
| Cicaloni V, Salvini L, Vitalini S, Garzoli S | Chemical Profiling and Characterization of Different Cultivars of Cannabis sativa L. Inflorescences by SPME-GC-MS and UPLC-MS. | Separations. 2022 Apr 2;9(4):90. | Link |
| Galderisi S, Milella MS, Rossi M, Cicaloni V, Rossi R, Giustarini D, Spiga O, Tinti L, Salvini L, Tinti C, Braconi D. | Homogentisic acid induces autophagy alterations leading to chondroptosis in human chondrocytes: Implications in Alkaptonuria. | Archives of Biochemistry and Biophysics. 2022 Mar 15;717:109137. | Link |
| Visibelli A, Cicaloni V, Spiga O, Santucci A. | Computational Approaches Integrated In A Digital Ecosystem Platform For A Rare Disease. | Frontiers in Molecular Medicine.:1. published: 22 February 2022 | Link |
| Karmakar M, Cicaloni V, Rodrigues CH, Spiga O, Santucci A, Ascher DB. | HGDiscovery: An online tool providing functional and phenotypic information on novel variants of homogentisate 1, 2-dioxigenase. | Current Research in Structural Biology. 2022 Jan 1;4:271-7. | Link |
| Autori | Titolo | Testata | DOI |
|---|---|---|---|
| Barbera S, Raucci L, Tassone G, Tinti L, Prischi F, Santucci A, Mongiat M, Tosi GM, Galvagni F, Dimberg A, Pozzi C, Orlandini M. | Dimerization of the C-type lectin-like receptor CD93 promotes its binding to Multimerin-2 in endothelial cells. Int J Biol Macromol. | Int J Biol Macromol. 2023 Jan 1:224:453-464 | Link |
| Andreano E, Paciello I, Pierleoni G, Piccini G, Abbiento V, Antonelli G, Pileri P, Manganaro N, Pantano E, Maccari G, Marchese S, Donnici L, Benincasa L, Giglioli G, Leonardi M, De Santi C, Fabbiani M, Rancan I, Tumbarello M, Montagnani F, Sala C, Medini D, De Francesco R, Montomoli E, Rappuoli R. | B cell analyses after SARS-CoV-2 mRNA third vaccination reveals a hybrid immunity like antibody response. | Nat Commun. 2023 Jan 4;14(1):53 | Link |
| Barker DJ, Maccari G, Georgiou X, Cooper MA, Flicek P, Robinson J, Marsh SGE. | The IPD-IMGT/HLA Database. | Nucleic Acids Res. 2023 Jan 6;51(D1):D1053-D1060 | Link |
| Garzoli S, Cicaloni V, Salvini L, Trespidi G, Iriti M, Vitalini S. | SPME-GC-MS Analysis of the Volatile Profile of Three Fresh Yarrow (Achillea millefolium L.) Morphotypes from Different Regions of Northern Italy. | Separations 2023, 10(1), 51 | Link |
| Siena E, Schiavetti F, Borgogni E, Taccone M, Faenzi E, Brazzoli M, Aprea S, Bardelli M, Volpini G, Buricchi F, Sammicheli C, Tavarini S, Bechtold V, Blohmke CJ, Cardamone D, De Intinis C, Gonzalez-Lopez A, O'Hagan DT, Nuti S, Seidl C, Didierlaurent AM, Bertholet S, D'Oro U, Medini D, Finco O. | Systems analysis of human responses to an aluminium hydroxide-adsorbed TLR7 agonist (AS37) adjuvanted vaccine reveals a dose-dependent and specific activation of the interferon-mediated antiviral response. | Vaccine. 2023 Jan 16;41(3):724-734 | Link |
| Vitalini S, Di Martile M, Cicaloni V, Iannone M, Salvini L, Del Bufalo D, Iriti M, Garzoli S. | Volatile and Non-Volatile Content Determination and Biological Activity Evaluation of Fresh Humulus lupulus L. (cv. Chinook) Leaves and Inflorescences. | Separations 2023, 10(2), 91 | Link |
| Onnis A, Andreano E, Cassioli C, Finetti F, Della Bella C, Staufer O, Pantano E, Abbiento V, Marotta G, D'Elios MM, Rappuoli R, Baldari CT. | SARS-CoV-2 Spike protein suppresses CTL-mediated killing by inhibiting immune synapse assembly. | J Exp Med. 2023 Feb 6;220(2):e20220906 | Link |
| Ptak CP, Hsieh CL, Garnett JA, Rappuoli R, Lin YP. | Editorial: Intersection of biophysical and structural approaches in vaccine design. | Front Mol Biosci. 2023 Feb 14:10:1142656 | Link |
| Ahmad E, Mitra A, Ahmed W, Mahapatra V, Hegde SR, Sala C, Cole ST, Nagaraja V. | Rho-dependent transcription termination is the dominant mechanism in Mycobacterium tuberculosis. | Biochim Biophys Acta Gene Regul Mech. 2023 Jun;1866(2):194923 | Link |
| Rappuoli R, Young P, Ron E, Pecetta S, Pizza M. | Save the microbes to save the planet. A call to action of the International Union of the Microbiological Societies (IUMS). | One Health Outlook. 2023 Mar 6;5(1):5 | Link |
| Andreano E, Paciello I, Pierleoni G, Maccari G, Antonelli G, Abbiento V, Pileri P, Benincasa L, Giglioli G, Piccini G, De Santi C, Sala C, Medini D, Montomoli E, Maes P, Rappuoli R. | mRNA vaccines and hybrid immunity use different B cell germlines against Omicron BA.4 and BA.5. | Nat Commun. 2023 Mar 28;14(1):1734 | Link |
| Baldari CT, Onnis A, Andreano E, Del Giudice G, Rappuoli R. | Emerging roles of SARS-CoV-2 Spike-ACE2 in immune evasion and pathogenesis. | Trends Immunol. 2023 Jun;44(6):424-434 | Link |
| Tinti L, Cicaloni V, Nezi P, Isoldi G, Etiope P, Barlozzini B, Pecorari R, Salvini L. | Hydroxyanthracene derivates citotoxicity: A differential evaluation between single molecule and whole plant extract. | Front Plant Sci. 2023 Apr 11:14:1166075 | Link |
| Grandi A, Tomasi M, Ullah I, Bertelli C, Vanzo T, Accordini S, Gagliardi A, Zanella I, Benedet M, Corbellari R, Lascio GD, Tamburini S, Caproni E, Croia L, Ravà M, Fumagalli V, Lucia PD, Marotta D, Sala E, Iannacone M, Kumar P, Mothes W, Uchil PD, Cherepanov P, Bolognesi M, Pizzato M, Grandi G. | Immunogenicity and pre-clinical efficacy of an OMV-based SARS-CoV-2 vaccine. | Res Sq. 2023 May 25:rs.3.rs-2788726 | Link |
| Caproni E, Corbellari R, Tomasi M, Isaac SJ, Tamburini S, Zanella I, Grigolato M, Gagliardi A, Benedet M, Baraldi C, Croia L, Di Lascio G, Berti A, Valensin S, Bellini E, Parri M, Grandi A, Grandi G. | Anti-Tumor Efficacy of In Situ Vaccination Using Bacterial Outer Membrane Vesicles. | Cancers (Basel)u. 2023 Jun 24;15(13):3328 | Link |
| Stazzoni S, Troisi M, Abbiento V, Sala C, Andreano E, Rappuoli R. | High-throughput bactericidal assays for monoclonal antibody screening against antimicrobial resistant Neisseria gonorrhoeae. | Front Microbiol. 2023 Aug 16:14:1243427 | Link |
| Pambianchi E, Hagenberg Z, Pecorelli A, Pasqui A, Therrien JP, Valacchi G. | Tension as a key factor in skin responses to pollution. | Sci Rep. 2023 Sep 25;13(1):16013 | Link |
| Grandi A, Tomasi M, Ullah I, Bertelli C, Vanzo T, Accordini S, Gagliardi A, Zanella I, Benedet M, Corbellari R, Di Lascio G, Tamburini S, Caproni E, Croia L, Ravà M, Fumagalli V, Di Lucia P, Marotta D, Sala E, Iannacone M, Kumar P, Mothes W, Uchil PD, Cherepanov P, Bolognesi M, Pizzato M, Grandi G. | Immunogenicity and Pre-Clinical Efficacy of an OMV-Based SARS-CoV-2 Vaccine. | Vaccines (Basel). 2023 Sep 29;11(10):1546 | Link |
| Silva-Moraes V, Souquette A, Sautto GA, Paciello I, Antonelli G, Andreano E, Rappuoli R, Teixeira-Carvalho A, Ross TM. | Prior SARS-CoV-2 Infection Enhances Initial mRNA Vaccine Response with a Lower Impact on Long-Term Immunity. | Immunohorizons. 2023 Oct 1;7(10):635-651 | Link |
| Tamburini S, Zhang Y, Gagliardi A, Di Lascio G, Caproni E, Benedet M, Tomasi M, Corbellari R, Zanella I, Croia L, Grandi G, Müller M, Grandi A. | Bacterial Outer Membrane Vesicles as a Platform for the Development of a Broadly Protective Human Papillomavirus Vaccine Based on the Minor Capsid Protein L2. | Vaccines (Basel). 2023 Oct 11;11(10):1582 | Link |
| Croia L, Boscato Sopetto G, Zanella I, Caproni E, Gagliardi A, Tamburini S, König E, Benedet M, Di Lascio G, Corbellari R, Grandi A, Tomasi M, Grandi G. | Immunogenicity of Escherichia coli Outer Membrane Vesicles: Elucidation of Humoral Responses against OMV-Associated Antigens. | Membranes (Basel). 2023 Nov 16;13(11):882 | Link |
| Troisi M, Fabbrini M, Stazzoni S, Viviani V, Carboni F, Abbiento V, Fontana LE, Tomei S, Audagnotto M, Santini L, Spagnuolo A, Antonelli G, Paciello I, Vacca F, Cardamone D, Marini E, Mokhtary P, Finetti F, Giusti F, Bodini M, Torricelli G, Limongi C, Del Vecchio M, Favaron S, Tavarini S, Sammicheli C, Rossi A, Mandelli AP, Fortini P, Caffarelli C, Gonnelli S, Nuti R, Baldari CT, Sala C, Tagliabue A, Savino S, Brunelli B, Norais N, Frigimelica E, Bardelli M, Pizza M, Margarit I, Delany I, Finco O, Andreano E, Rappuoli R. | Human monoclonal antibodies reveal subdominant gonococcal and meningococcal cross-protective antigens. | bioRxiv preprint; this version posted December 8, 2023 | Link |
| Pasqui A, Cicaloni V, Tinti L, Guiotto A, Tinti C, Mori A, Bruttini M, Hayek J, Pecorelli A, Salvini L, Valacchi G. | A proteomic approach to investigate the role of the MECP2 gene mutation in Rett syndrome redox regulatory pathways. | Arch Biochem Biophys. 2024 Feb:752:109860 | Link |
| Simon-Molas H, Del Prete R, Kabanova A. | Glucose metabolism in B cell malignancies: a focus on glycolysis branching pathways. | Mol Oncol. 2023 Dec 19 | Link |
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