{"id":19882,"date":"2023-03-30T16:33:57","date_gmt":"2023-03-30T14:33:57","guid":{"rendered":"https:\/\/www.toscanalifesciences.org\/?p=19882"},"modified":"2023-03-30T16:36:19","modified_gmt":"2023-03-30T14:36:19","slug":"tls-nuovo-erc-advanced-grant-a-rino-rappuoli","status":"publish","type":"post","link":"https:\/\/www.toscanalifesciences.org\/it\/news-e-eventi\/tls-nuovo-erc-advanced-grant-a-rino-rappuoli\/","title":{"rendered":"TLS: nuovo ERC Advanced Grant a Rino Rappuoli"},"content":{"rendered":"<p>Nuovo <strong><a href=\"https:\/\/erc.europa.eu\/apply-grant\/advanced-grant\">ERC Advanced Grant<\/a> <\/strong>per <strong>Rino Rappuoli.<\/strong> Il prestigioso finanziamento \u00e8 stato assegnato dall\u2019<strong>European Research Council<\/strong> (ERC) al microbiologo di fama internazionale, gi\u00e0 coordinatore scientifico del<strong> MAD Lab di Toscana Life Sciences<\/strong> e Direttore scientifico della Fondazione Biotecnopolo di Siena, per portare avanti un progetto di ricerca dedicato allo sviluppo di nuovi anticorpi monoclonali e vaccini contro SARS-CoV-2, sia varianti gi\u00e0 note del virus sia varianti che potrebbero svilupparsi in futuro. L\u2019attivit\u00e0 di ricerca sar\u00e0 condotta presso la Fondazione Toscana Life Sciences (TLS), nel ruolo di host institution. Il progetto dal titolo PROACTIVE, acronimo di &#8220;PROposing Action to ConTrol and Impede betacoronaVirus Emergencies&#8221;, si concentrer\u00e0 sullo studio di anticorpi monoclonali umani a scopo sia profilattico sia terapeutico come risposta al virus SARS-CoV-2 nelle sue varianti, per combattere i coronavirus che potrebbero rivelarsi pericolosi e per i quali attualmente non esiste ancora nessuna soluzione efficace. Il nuovo progetto ha una durata di cinque anni e verr\u00e0 finanziato con circa 2.5 milioni di euro.<\/p>\n<p>Il secondo Grant a Rappuoli si aggiunge a quello assegnato nel 2018 sempre dall\u2019European Research Council, che aveva riconosciuto allo scienziato senese un finanziamento di <strong>2.5 milioni di euro<\/strong> per il progetto vAMRes (Vaccines as a remedy against Anti-Microbial Resistance) \u2013 \u201cIsolation and screening of human monoclonal antibodies against AMR for therapy and for discovery of novel vaccine antigens\u201d con l\u2019obiettivo di sviluppare anticorpi monoclonali e vaccini in grado di rispondere alla resistenza batterica agli antibiotici. Rino Rappuoli \u00e8 uno dei 64 scienziati che quest&#8217;anno hanno ricevuto un ERC Advanced Grant nell\u2019area delle life sciences (uno dei 218 vincitori su 1650 progetti candidati in tutte le aree).<\/p>\n<p>Un nuovo riconoscimento, quello a Rino Rappuoli, che si aggiunge ai tre ERC, per un totale di oltre 10 milioni di euro che, negli anni, attraverso l\u2019European Reserch Council hanno sostenuto altrettante attivit\u00e0 di ricerca che sono state sviluppare all\u2019interno di TLS: il Progetto OMVac (e relativo PoC \u2013 Proof of Concept) per la creazione di un nuovo ceppo batterico (\u201cVaccinobacter\u201d) per la produzione di vaccini multivalenti contro malattie infettive e tumori; il Progetto vAMRes per la realizzazione di anticorpi in grado di rispondere alla resistenza batterica agli antibiotici e il progetto VACCIBIOME volto a investigare il ruolo del microbiota intestinale sull\u2019efficacia di vaccini antitumorali.<\/p>\n<p>L\u2019<strong>European Research Council<\/strong> (ERC) \u00e8 stato istituito nel febbraio 2007 dalla Commissione europea nell\u2019ambito del Settimo programma quadro per la ricerca (7\u00b0 PQ), al fine di provvedere all\u2019attuazione del programma specifico \u2018Idee\u2019 e di sostenere la ricerca svolta su iniziativa dei ricercatori. I bandi dell\u2019ERC sono tra i pi\u00f9 competitivi a livello europeo e supportano la ricerca di frontiera, finanziando progetti visionari e altamente innovativi, proposti da ricercatori e ricercatrici di elevato profilo a livello internazionale, in varie aree di ricerca scientifica.<\/p>\n<p><a href=\"https:\/\/erc.europa.eu\/news-events\/news\/erc-2022-advanced-grants-results\"><strong>Qui al link<\/strong><\/a> \u00e8 possibile trovare il press kit dell\u2019ERC.<\/p>\n<p>&nbsp;<\/p>\n<p>&nbsp;<\/p>\n","protected":false},"excerpt":{"rendered":"<p>TLS \u00e8 Host Institution del progetto quinquennale PROACTIVE, finanziato con circa 2.5 milioni di euro. <\/p>\n","protected":false},"author":10,"featured_media":19883,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[9],"tags":[],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v23.2 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>TLS: nuovo ERC Advanced Grant a Rino Rappuoli - 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