{"id":13228,"date":"2022-01-30T09:59:57","date_gmt":"2022-01-30T08:59:57","guid":{"rendered":"https:\/\/tls.giangocomunicazione.it\/?page_id=13228"},"modified":"2026-08-05T11:24:43","modified_gmt":"2026-08-05T09:24:43","slug":"servizi-di-ricerca-conto-terzi","status":"publish","type":"page","link":"https:\/\/www.toscanalifesciences.org\/it\/servizi-di-ricerca-conto-terzi\/","title":{"rendered":"Servizi di ricerca conto terzi"},"content":{"rendered":"<section class=\"l-section wpb_row us_custom_6a6ddcc9 main_row_articolo height_medium width_full\"><div class=\"l-section-h i-cf\"><div class=\"g-cols vc_row via_flex valign_top type_default stacking_default\"><div class=\"vc_col-sm-12 wpb_column vc_column_container\"><div class=\"vc_column-inner\"><div class=\"wpb_wrapper\"><div class=\"w-image img-fullwidth align_none\"><div class=\"w-image-h\"><img loading=\"lazy\" decoding=\"async\" width=\"2500\" height=\"450\" src=\"https:\/\/www.toscanalifesciences.org\/wp-content\/uploads\/2022\/07\/Servizi-di-ricerca-conto-terzi_Testata-Pagine-interna_2500x450_2022-04-08.jpg\" class=\"attachment-full size-full\" alt=\"\" srcset=\"https:\/\/www.toscanalifesciences.org\/wp-content\/uploads\/2022\/07\/Servizi-di-ricerca-conto-terzi_Testata-Pagine-interna_2500x450_2022-04-08.jpg 2500w, https:\/\/www.toscanalifesciences.org\/wp-content\/uploads\/2022\/07\/Servizi-di-ricerca-conto-terzi_Testata-Pagine-interna_2500x450_2022-04-08-300x54.jpg 300w, https:\/\/www.toscanalifesciences.org\/wp-content\/uploads\/2022\/07\/Servizi-di-ricerca-conto-terzi_Testata-Pagine-interna_2500x450_2022-04-08-1024x184.jpg 1024w, https:\/\/www.toscanalifesciences.org\/wp-content\/uploads\/2022\/07\/Servizi-di-ricerca-conto-terzi_Testata-Pagine-interna_2500x450_2022-04-08-1920x346.jpg 1920w\" sizes=\"(max-width: 2500px) 100vw, 2500px\" \/><\/div><\/div><\/div><\/div><\/div><\/div><\/div><\/section><section class=\"l-section wpb_row us_custom_e3cbe9f3 height_medium\"><div class=\"l-section-h i-cf\"><div class=\"g-cols vc_row via_flex valign_top type_default stacking_default\"><div class=\"vc_col-sm-12 wpb_column vc_column_container\"><div class=\"vc_column-inner\"><div class=\"wpb_wrapper\">[vc_custom_heading text=&#8221;Servizi di ricerca conto terzi&#8221; font_container=&#8221;tag:h2|text_align:center&#8221; use_theme_fonts=&#8221;yes&#8221; css=&#8221;%7B%22default%22%3A%7B%22color%22%3A%22_alt_content_secondary%22%2C%22font-weight%22%3A%22400%22%2C%22text-transform%22%3A%22uppercase%22%7D%7D&#8221;]<div class=\"wpb_text_column\"><div class=\"wpb_wrapper\"><p>Grazie alle competenze e all\u2019esperienza del proprio personale tecnico-scientifico la <strong>Fondazione TLS<\/strong> supporta ricercatori e aziende nella messa a punto delle <strong>metodiche analitiche<\/strong> e nella conduzione di <strong>attivit\u00e0 sperimentali<\/strong> in vitro. A tal fine, TLS mette a disposizione <strong>know-how<\/strong>, <strong>piattaforme tecnologiche<\/strong> e <strong>strumentazioni analitiche<\/strong> per attivit\u00e0 di ricerca in campo biologico e molecolare.<\/p>\n<p>Nel tempo, \u00e8 stata possibile una sempre maggiore strutturazione dei <strong>servizi di ricerca<\/strong> offerti grazie all\u2019implementazione di nuove piattaforme.<\/p>\n<p><strong>I principali servizi e le<\/strong> <strong>piattaforme tecnologiche<\/strong>:<\/p>\n<ul>\n<li><strong>PROTEOMICA, METABOLOMICA E PROFILING MOLECOLARE<\/strong> (spettrometro di massa ad alta risoluzione Q-Exactive HF-X, accoppiato ad UPLC a nanoflussi): sperimentazione di protocolli \u201ccustom\u201d per matrici di varia origine;<\/li>\n<li><strong>ANALISI CAMPIONI DI DERIVAZIONE BOTANICA E\/O NUTRACEUTICA<\/strong> (spettrometro di massa Q-Exactive Plus, accoppiato ad UPLC dotato di un rivelatore DAD);<\/li>\n<li><strong>Sviluppo di modelli cellulari custom \u201cin vitro\u201d<\/strong> per test di tossicit\u00e0, efficacia e assorbimento di <strong>prodotti di origine botanica e\/o nutraceutica;<\/strong><\/li>\n<li><strong>Opera Phenix HIGH CONTENT SCREENING System &#8211;<\/strong> strumento di eccellenza per analisi high-throughput per screening di fenotipi e analisi su modelli complessi di patologie, esperimenti \u201clive\u201d su cellule, colture primarie, colture cellulari 3D e microtessuti;<\/li>\n<li><strong>BSL3 \u2013 LABORATORIO DI CONTENIMENTO<\/strong> di Agenti PATOGENI di LIVELLO 3;<\/li>\n<li><strong>BIOINFORMATICA<\/strong> &#8211; offre approcci consolidati di analisi bioinformatica, recentemente implementati con metodi di data mining basati su reti neurali e AI, per lo sviluppo di pipeline customizzate per l\u2019elaborazione di dati proteomici e metabolomici derivanti dalla Spettrometria di Massa;<\/li>\n<li><strong>GENERAZIONE e PRODUZIONE ANTICORPI<\/strong> &#8211; Produzione e purificazione di proteine ricombinanti in cellule di mammifero. &#8211; Studi di immunogenicit\u00e0 e produzione di anticorpi policlonali da topo, coniglio. &#8211; Identificazione e clonaggio di anticorpi monoclonali da uomo, topo e coniglio mediante tecnologia a singola cellula.\u00a0 &#8211; Espressione e purificazione di anticorpi monoclonali ricombinanti.\u00a0\u00a0 &#8211; Next-generation antibody engineering (inclusi bispecifici) &#8211; Saggi di legame. &#8211; Real-time protein-protein\/protein-small molecule kinetics (ka, kd, KD), concentration\/titer assays (IgG), and epitope mapping. &#8211; Developability (stabilit\u00e0 termica, stabilit\u00e0 colloidale, applicazione di tecnologie di dinamica molecolare e deep learning per migliorare binding, stabilita&#8217; ed espressione) &#8211; Attivit\u00e0 funzionale degli anticorpi monoclonali in vitro in ambiente BSL2 e BSL3;<\/li>\n<li><strong>GENE EDITING &#8211;<\/strong> Tecnologia CRISPR\/Cas9 in linee cellulari e cellule primarie difficili da manipolare.<\/li>\n<\/ul>\n<p><a class=\"btn_contattaci\" href=\"\/contatti\/\">Contattaci<\/a><\/p>\n<\/div><\/div><\/div><\/div><\/div><\/div><\/div><\/section><section class=\"l-section wpb_row us_custom_8a398476 row_scarica_presentazione height_auto with_img\"><div class=\"l-section-img\" data-img-width=\"1244\" data-img-height=\"708\" style=\"background-image: url(https:\/\/www.toscanalifesciences.org\/wp-content\/uploads\/2021\/02\/demo-blue-bg.jpg);\"><\/div><div class=\"l-section-h i-cf\"><div class=\"g-cols vc_row via_flex valign_top type_default stacking_default\"><div class=\"vc_col-sm-12 wpb_column vc_column_container\"><div class=\"vc_column-inner\"><div class=\"wpb_wrapper\">[vc_raw_html]JTVCZ25ld3NsZXR0ZXJ0bHMlNUQlNUIlMkZnbmV3c2xldHRlcnRscyU1RA==[\/vc_raw_html]<\/div><\/div><\/div><\/div><\/div><\/section><section class=\"l-section wpb_row us_custom_674bb2f6 us_animate_this height_medium\" id=\"mid-sec-title-hanno-scelto\"><div class=\"l-section-h i-cf\"><div class=\"g-cols vc_row via_flex valign_top type_default stacking_default\"><div class=\"vc_col-sm-12 wpb_column vc_column_container\"><div class=\"vc_column-inner\"><div class=\"wpb_wrapper\">[vc_custom_heading text=&#8221;I servizi di TLS&#8221; font_container=&#8221;tag:h2|text_align:center&#8221; use_theme_fonts=&#8221;yes&#8221; css=&#8221;%7B%22default%22%3A%7B%22color%22%3A%22_content_primary%22%2C%22font-weight%22%3A%22400%22%2C%22text-transform%22%3A%22uppercase%22%7D%7D&#8221;][vc_custom_heading text=&#8221;visita le altre sezioni&#8221; font_container=&#8221;tag:h3|text_align:center&#8221; use_theme_fonts=&#8221;yes&#8221; css=&#8221;%7B%22default%22%3A%7B%22color%22%3A%22%23404040%22%2C%22text-align%22%3A%22center%22%7D%7D&#8221;]<\/div><\/div><\/div><\/div><\/div><\/section><section class=\"l-section wpb_row us_custom_5709a925 centering_columns us_animate_this height_auto\"><div class=\"l-section-h i-cf\"><div class=\"g-cols vc_row via_flex valign_top type_default stacking_default\"><div class=\"vc_col-sm-4 wpb_column vc_column_container col_trova_casa\"><div class=\"vc_column-inner\"><div class=\"vc_column-overlay\" style=\"background:rgba(255,255,255,0.65)\"><\/div><div class=\"wpb_wrapper\"><div class=\"w-image align_none\"><div class=\"w-image-h\"><img loading=\"lazy\" decoding=\"async\" width=\"1613\" height=\"1075\" src=\"https:\/\/www.toscanalifesciences.org\/wp-content\/uploads\/2022\/04\/Servizi-per-incubate_TLS-18.jpg\" class=\"attachment-full size-full\" alt=\"\" \/><\/div><\/div>[vc_custom_heading text=&#8221;Servizi del Bioincubatore&#8221; font_container=&#8221;tag:h2|text_align:center&#8221; use_theme_fonts=&#8221;yes&#8221; css=&#8221;%7B%22default%22%3A%7B%22color%22%3A%22%232d70a6%22%7D%7D&#8221;]<div class=\"wpb_text_column\"><div class=\"wpb_wrapper\"><p style=\"text-align: center;\"><span style=\"font-weight: 400;\">La<strong> Fondazione TLS<\/strong> mette a disposizione <strong>spazi<\/strong>, <strong>facility tecnologiche<\/strong> e <strong>servizi<\/strong> necessari alla nascita, allo sviluppo e all\u2019accesso al mercato di un\u2019impresa nel settore<strong> scienze della vita<\/strong>.<\/span><\/p>\n<\/div><\/div>[vc_raw_html el_class=&#8221;btn_center_scarica&#8221;]JTNDYSUyMGhyZWYlM0QlMjIlMkZzZXJ2aXppLWRlbC1iaW9pbmN1YmF0b3JlJTJGJTIyJTIwY2xhc3MlM0QlMjJzY2FyaWNhX2J0biUyMiUzRVZhaSUyMCUzQ2klMjBjbGFzcyUzRCUyMmZhcyUyMGZhLWFuZ2xlLXJpZ2h0JTIyJTNFJTNDJTJGaSUzRSUzQyUyRmElM0U=[\/vc_raw_html]<\/div><\/div><\/div><\/div><\/div><\/section>\n","protected":false},"excerpt":{"rendered":"[vc_custom_heading text=\"Servizi di ricerca conto terzi\" font_container=\"tag:h2|text_align:center\" use_theme_fonts=\"yes\" css=\"%7B%22default%22%3A%7B%22color%22%3A%22_alt_content_secondary%22%2C%22font-weight%22%3A%22400%22%2C%22text-transform%22%3A%22uppercase%22%7D%7D\"]Grazie alle competenze e all\u2019esperienza del proprio personale tecnico-scientifico la Fondazione TLS...","protected":false},"author":1,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_acf_changed":false,"footnotes":""},"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v23.2 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Servizi di ricerca conto terzi - Toscana Life Sciences<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.toscanalifesciences.org\/it\/servizi-di-ricerca-conto-terzi\/\" \/>\n<meta property=\"og:locale\" content=\"it_IT\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Servizi di ricerca conto terzi - Toscana Life Sciences\" \/>\n<meta property=\"og:url\" content=\"https:\/\/www.toscanalifesciences.org\/it\/servizi-di-ricerca-conto-terzi\/\" \/>\n<meta property=\"og:site_name\" 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