{"id":16643,"date":"2022-01-30T09:59:57","date_gmt":"2022-01-30T08:59:57","guid":{"rendered":"https:\/\/tls.giangocomunicazione.it\/servizi-di-ricerca-conto-terzi\/"},"modified":"2026-08-05T14:00:46","modified_gmt":"2026-08-05T12:00:46","slug":"research-services-for-third","status":"publish","type":"page","link":"https:\/\/www.toscanalifesciences.org\/en\/research-services-for-third\/","title":{"rendered":"Research Services for Third Parties"},"content":{"rendered":"<section class=\"l-section wpb_row us_custom_98786371 main_row_articolo us_animate_this height_medium width_full\"><div class=\"l-section-h i-cf\"><div class=\"g-cols vc_row via_flex valign_top type_default stacking_default\"><div class=\"vc_col-sm-12 wpb_column vc_column_container\"><div class=\"vc_column-inner\"><div class=\"wpb_wrapper\"><div class=\"w-image img-fullwidth align_none\"><div class=\"w-image-h\"><img loading=\"lazy\" decoding=\"async\" width=\"2500\" height=\"450\" src=\"https:\/\/www.toscanalifesciences.org\/wp-content\/uploads\/2022\/07\/Servizi-di-ricerca-conto-terzi_Testata-Pagine-interna_2500x450_2022-04-08.jpg\" class=\"attachment-full size-full\" alt=\"\" srcset=\"https:\/\/www.toscanalifesciences.org\/wp-content\/uploads\/2022\/07\/Servizi-di-ricerca-conto-terzi_Testata-Pagine-interna_2500x450_2022-04-08.jpg 2500w, https:\/\/www.toscanalifesciences.org\/wp-content\/uploads\/2022\/07\/Servizi-di-ricerca-conto-terzi_Testata-Pagine-interna_2500x450_2022-04-08-300x54.jpg 300w, https:\/\/www.toscanalifesciences.org\/wp-content\/uploads\/2022\/07\/Servizi-di-ricerca-conto-terzi_Testata-Pagine-interna_2500x450_2022-04-08-1024x184.jpg 1024w, https:\/\/www.toscanalifesciences.org\/wp-content\/uploads\/2022\/07\/Servizi-di-ricerca-conto-terzi_Testata-Pagine-interna_2500x450_2022-04-08-1920x346.jpg 1920w\" sizes=\"(max-width: 2500px) 100vw, 2500px\" \/><\/div><\/div><\/div><\/div><\/div><\/div><\/div><\/section><section class=\"l-section wpb_row us_custom_dc11b89f us_animate_this height_medium\" id=\"sec-nostra-proposta\"><div class=\"l-section-h i-cf\"><div class=\"g-cols vc_row via_flex valign_top type_default stacking_default\"><div class=\"vc_col-sm-12 wpb_column vc_column_container\"><div class=\"vc_column-inner\"><div class=\"wpb_wrapper\">[vc_custom_heading text=&#8221;RESEARCH SERVICES FOR THIRD PARTIES&#8221; font_container=&#8221;tag:h2|text_align:center&#8221; use_theme_fonts=&#8221;yes&#8221; css=&#8221;%7B%22default%22%3A%7B%22color%22%3A%22%23015294%22%2C%22font-weight%22%3A%22400%22%2C%22text-transform%22%3A%22uppercase%22%7D%7D&#8221;]<div class=\"wpb_text_column\"><div class=\"wpb_wrapper\"><p>Owing to the competencies and experience of its technical and scientific staff, the Fondazione TLS supports researchers and companies in the development of analytical methods and in carrying out <em>in vitro <\/em>experiments. To this end, TLS provides know-how, technological platforms and analytical instruments for research activities in the biological and molecular fields.<\/p>\n<p>Over time, it has been possible to increasingly structure the <strong>research services<\/strong> offered thanks to the implementation of new technological platforms.<\/p>\n<p>The main <strong>services <\/strong>and <strong>technological platforms<\/strong> comprise:<\/p>\n<ul>\n<li><strong>PROTEOMICS, METABOLOMICS AND MOLECULAR PROFILING<\/strong> (Q-Exactive HF-X high-resolution mass spectrometer, combined with nanoflow UPLC): experimentation of custom protocols for matrices of various origins<\/li>\n<li><strong>ANALYSIS OF SAMPLES DERIVED FROM BOTANICALS AND\/OR NUTRACEUTICALS<\/strong> (Q-Exactive Plus mass spectrometer, coupled with UPLC fitted with a DAD detector);<\/li>\n<li><strong>Testing of custom &#8220;in vitro&#8221; protocols<\/strong> for toxicity, efficacy and absorption of botanical and \/ or nutraceutical products<\/li>\n<li><strong>Opera Phenix HIGH CONTENT SCREENING System<\/strong>. Hi-level technology for high-throughput analysis for phenotype screening and analysis on complex models of pathologies, \u201clive\u201d experiments on cells, primary cultures, 3D cell cultures and micro-tissues.<\/li>\n<li><strong>BIOINFORMATICS<\/strong> offers established bioinformatics analysis approaches, recently enhanced with data mining methods based on neural networks and AI, for the development of customised pipelines for processing proteomic and metabolomic data derived from mass spectrometry.<\/li>\n<li><strong>ANTIBODY GENERATION AND PRODUCTION<\/strong> &#8211; Production and purification of recombinant proteins in mammalian cells. &#8211; Immunogenicity studies and production of polyclonal antibodies from mice and rabbits. &#8211; Identification and cloning of monoclonal antibodies from humans, mice and rabbits using single-cell technology. &#8211; Expression and purification of recombinant monoclonal antibodies. &#8211; Next-generation antibody engineering (including bispecific antibodies) &#8211; Binding assays. &#8211; Real-time protein-protein\/protein-small molecule kinetics (ka, kd, KD), concentration\/titer assays (IgG), and epitope mapping. &#8211; Developability (thermal stability, colloidal stability, application of molecular dynamics and deep learning technologies to improve binding, stability and expression) &#8211; In vitro functional activity of monoclonal antibodies in BSL2 and BSL3 environments.<\/li>\n<li><strong>Next Generation Sequencing (NGS)<\/strong> &#8211; (Novaseq 6000, a new-generation system for gene sequencing)<\/li>\n<li><strong>BSL-3<\/strong> \u2013 PATHOGEN CONTAINMENT LEVEL 3 LABORATORY<\/li>\n<\/ul>\n<p><a class=\"btn_contattaci\" href=\"\/en\/contacts\/\">Contact us<\/a><\/p>\n<\/div><\/div><\/div><\/div><\/div><\/div><\/div><\/section><section class=\"l-section wpb_row us_custom_636189fa row_scarica_presentazione us_animate_this height_auto with_img\"><div class=\"l-section-img\" data-img-width=\"1244\" data-img-height=\"708\" style=\"background-image: url(https:\/\/www.toscanalifesciences.org\/wp-content\/uploads\/2021\/02\/demo-blue-bg.jpg);\"><\/div><div class=\"l-section-h i-cf\"><div class=\"g-cols vc_row via_flex valign_top type_default stacking_default\"><div class=\"vc_col-sm-12 wpb_column vc_column_container\"><div class=\"vc_column-inner\"><div class=\"wpb_wrapper\">[vc_raw_html]JTVCZ25ld3NsZXR0ZXJ0bHMlNUQlNUIlMkZnbmV3c2xldHRlcnRscyU1RA==[\/vc_raw_html]<\/div><\/div><\/div><\/div><\/div><\/section><section class=\"l-section wpb_row us_custom_f74ef8b2 us_animate_this height_medium\" id=\"mid-sec-title-hanno-scelto\"><div class=\"l-section-h i-cf\"><div class=\"g-cols vc_row via_flex valign_top type_default stacking_default\"><div class=\"vc_col-sm-12 wpb_column vc_column_container\"><div class=\"vc_column-inner\"><div class=\"wpb_wrapper\">[vc_custom_heading text=&#8221;TLS Services&#8221; font_container=&#8221;tag:h2|text_align:center&#8221; use_theme_fonts=&#8221;yes&#8221; css=&#8221;%7B%22default%22%3A%7B%22color%22%3A%22_content_primary%22%2C%22font-weight%22%3A%22400%22%2C%22text-transform%22%3A%22uppercase%22%7D%7D&#8221;][vc_custom_heading text=&#8221;visit the other sections&#8221; font_container=&#8221;tag:h3|text_align:center&#8221; use_theme_fonts=&#8221;yes&#8221; css=&#8221;%7B%22default%22%3A%7B%22color%22%3A%22%23404040%22%2C%22text-align%22%3A%22center%22%7D%7D&#8221;]<\/div><\/div><\/div><\/div><\/div><\/section><section class=\"l-section wpb_row us_custom_5709a925 centering_columns us_animate_this height_auto\"><div class=\"l-section-h i-cf\"><div class=\"g-cols vc_row via_flex valign_top type_default stacking_default\"><div class=\"vc_col-sm-4 wpb_column vc_column_container col_trova_casa\"><div class=\"vc_column-inner us_custom_ec019216 us_animate_this\"><div class=\"vc_column-overlay\" style=\"background:rgba(255,255,255,0.65)\"><\/div><div class=\"wpb_wrapper\"><div class=\"w-image align_none\"><div class=\"w-image-h\"><img loading=\"lazy\" decoding=\"async\" width=\"1811\" height=\"1047\" src=\"https:\/\/www.toscanalifesciences.org\/wp-content\/uploads\/2022\/04\/Servizi-per-incubate_TLS-18.jpg\" class=\"attachment-full size-full\" alt=\"\" srcset=\"https:\/\/www.toscanalifesciences.org\/wp-content\/uploads\/2022\/04\/Servizi-per-incubate_TLS-18.jpg 1811w, https:\/\/www.toscanalifesciences.org\/wp-content\/uploads\/2022\/04\/Servizi-per-incubate_TLS-18-300x173.jpg 300w, https:\/\/www.toscanalifesciences.org\/wp-content\/uploads\/2022\/04\/Servizi-per-incubate_TLS-18-1024x592.jpg 1024w, https:\/\/www.toscanalifesciences.org\/wp-content\/uploads\/2022\/04\/Servizi-per-incubate_TLS-18-692x400.jpg 692w\" sizes=\"(max-width: 1811px) 100vw, 1811px\" \/><\/div><\/div>[vc_custom_heading text=&#8221;Bioincubator Services&#8221; font_container=&#8221;tag:h2|text_align:center&#8221; use_theme_fonts=&#8221;yes&#8221; css=&#8221;%7B%22default%22%3A%7B%22color%22%3A%22%232d70a6%22%7D%7D&#8221;]<div class=\"wpb_text_column\"><div class=\"wpb_wrapper\"><p style=\"text-align: center;\">The Fondazione TLS provides the workspace, technological facilities and services required to set up a company operating in the life sciences sector.<\/p>\n<\/div><\/div>[vc_raw_html el_class=&#8221;btn_center_scarica&#8221;]JTNDYSUyMGhyZWYlM0QlMjIlMkZlbiUyRmluY3ViYXRvci1zZXJ2aWNlcyUyRiUyMiUyMGNsYXNzJTNEJTIyc2NhcmljYV9idG4lMjIlM0VSZWFkJTIwTW9yZSUyMCUzQ2klMjBjbGFzcyUzRCUyMmZhcyUyMGZhLWFuZ2xlLXJpZ2h0JTIyJTNFJTNDJTJGaSUzRSUzQyUyRmElM0U=[\/vc_raw_html]<\/div><\/div><\/div><\/div><\/div><\/section>\n","protected":false},"excerpt":{"rendered":"[vc_custom_heading text=\"RESEARCH SERVICES FOR THIRD PARTIES\" font_container=\"tag:h2|text_align:center\" use_theme_fonts=\"yes\" css=\"%7B%22default%22%3A%7B%22color%22%3A%22%23015294%22%2C%22font-weight%22%3A%22400%22%2C%22text-transform%22%3A%22uppercase%22%7D%7D\"]Owing to the competencies and experience of its technical and scientific staff,...","protected":false},"author":1,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_acf_changed":false,"footnotes":""},"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v23.2 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Research Services for Third Parties - Toscana Life Sciences<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.toscanalifesciences.org\/en\/research-services-for-third\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Research Services for Third Parties - Toscana Life Sciences\" \/>\n<meta property=\"og:url\" content=\"https:\/\/www.toscanalifesciences.org\/en\/research-services-for-third\/\" \/>\n<meta property=\"og:site_name\" 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