{"id":16244,"date":"2022-05-25T12:09:30","date_gmt":"2022-05-25T10:09:30","guid":{"rendered":"https:\/\/tls.giangocomunicazione.it\/?page_id=16244"},"modified":"2026-06-01T10:05:59","modified_gmt":"2026-06-01T08:05:59","slug":"research-projects","status":"publish","type":"page","link":"https:\/\/www.toscanalifesciences.org\/en\/research-projects\/","title":{"rendered":"Research Projects"},"content":{"rendered":"<section class=\"l-section wpb_row us_custom_631ad31c first-row-trovacasa us_animate_this height_medium width_full\"><div class=\"l-section-h i-cf\"><div class=\"g-cols vc_row via_flex valign_top type_default stacking_default\"><div class=\"vc_col-sm-12 wpb_column vc_column_container\"><div class=\"vc_column-inner\"><div class=\"wpb_wrapper\"><div class=\"w-image align_none\"><div class=\"w-image-h\"><img loading=\"lazy\" decoding=\"async\" width=\"2500\" height=\"450\" src=\"https:\/\/www.toscanalifesciences.org\/wp-content\/uploads\/2022\/07\/I-progetti-di-ricerca_Testata-Pagine-interna_2500x450_2022-04-08.jpg\" class=\"attachment-full size-full\" alt=\"\" srcset=\"https:\/\/www.toscanalifesciences.org\/wp-content\/uploads\/2022\/07\/I-progetti-di-ricerca_Testata-Pagine-interna_2500x450_2022-04-08.jpg 2500w, https:\/\/www.toscanalifesciences.org\/wp-content\/uploads\/2022\/07\/I-progetti-di-ricerca_Testata-Pagine-interna_2500x450_2022-04-08-300x54.jpg 300w, https:\/\/www.toscanalifesciences.org\/wp-content\/uploads\/2022\/07\/I-progetti-di-ricerca_Testata-Pagine-interna_2500x450_2022-04-08-1024x184.jpg 1024w, https:\/\/www.toscanalifesciences.org\/wp-content\/uploads\/2022\/07\/I-progetti-di-ricerca_Testata-Pagine-interna_2500x450_2022-04-08-1920x346.jpg 1920w\" sizes=\"(max-width: 2500px) 100vw, 2500px\" \/><\/div><\/div><\/div><\/div><\/div><\/div><\/div><\/section><section class=\"l-section wpb_row us_custom_f6aa785f us_animate_this height_medium\"><div class=\"l-section-h i-cf\"><div class=\"g-cols vc_row via_flex valign_top type_default stacking_default\"><div class=\"vc_col-sm-12 wpb_column vc_column_container\"><div class=\"vc_column-inner\"><div class=\"wpb_wrapper\">[vc_custom_heading text=&#8221;Research Projects&#8221; font_container=&#8221;tag:h2|text_align:center&#8221; use_theme_fonts=&#8221;yes&#8221; css=&#8221;%7B%22default%22%3A%7B%22color%22%3A%22%23015294%22%2C%22font-weight%22%3A%22400%22%2C%22text-transform%22%3A%22uppercase%22%7D%7D&#8221;]<div class=\"wpb_text_column us_custom_0728b4ce\"><div class=\"wpb_wrapper\"><p style=\"text-align: center;\"><strong>TLS<\/strong> is involved in an increasing number of <strong>research projects<\/strong> aimed at responding to major health challenges such as bacterial resistance to antibiotics or orphan diseases, as well as at investigating the mechanisms of progression and regression of leukemia and blood cancers or the effectiveness of the application of vaccines to immuno-oncology.<br \/>\nThe Foundation is currently the host institution of important research projects, three of which are funded by the <strong>European Research Council<\/strong> (ERC), one by the <strong>Wellcome Trust, <\/strong>one by the<strong> Wellcome Leap<\/strong> and one made possible thanks to funding from <strong>AIRC<\/strong> (Italian Association for Cancer Research).<br \/>\nIn particular, following the spread of the <strong>SARS-CoV-2 coronavirus<\/strong>, in March 2020 TLS promptly started the <strong>MAbCo19 project<\/strong> for the development of a cure for COVID-19, relying on the expertise of the <strong>MAD Lab<\/strong> and on important sources of funding.<br \/>\nTLS has also consolidated its third-party research and development activities, for which it is involved in important projects mainly related to the use of skills and expertise in proteomics.<\/p>\n<\/div><\/div><\/div><\/div><\/div><\/div><\/div><\/section><section class=\"l-section wpb_row us_custom_5709a925 row_trovacasa us_animate_this height_large width_full\"><div class=\"l-section-h i-cf\"><div class=\"g-cols vc_row via_flex valign_top type_default stacking_default\"><div class=\"vc_col-sm-6 wpb_column vc_column_container center-content-col\"><div class=\"vc_column-inner\"><div class=\"vc_column-overlay\" style=\"background:rgba(255,255,255,0.65)\"><\/div><div class=\"wpb_wrapper\">[vc_custom_heading text=&#8221;BOTANICALS LAB&#8221; font_container=&#8221;tag:h2|text_align:center&#8221; use_theme_fonts=&#8221;yes&#8221; css=&#8221;%7B%22default%22%3A%7B%22color%22%3A%22%232d70a6%22%7D%7D&#8221;]<div class=\"wpb_text_column\"><div class=\"wpb_wrapper\"><p>The <strong>Botanicals Lab<\/strong> is an laboratory that combines the regulatory expertise in food supplements of <strong>Linneus Consulting<\/strong> with the laboratory know-how and analytical research services for the Botanicals sector provided by the<strong> Mass Spectrometry Unit<\/strong> (MSU).<\/p>\n<\/div><\/div>[vc_raw_html el_class=&#8221;btn_center_scarica&#8221;]JTNDYSUyMGhyZWYlM0QlMjIlMkZlbiUyRnRscy1yZXNlYXJjaCUyRmJvdGFuaWNhbHMtbGFiJTJGJTIyJTIwY2xhc3MlM0QlMjJzY2FyaWNhX2J0biUyMiUzRVJlYWQlMjBtb3JlJTIwJTNDaSUyMGNsYXNzJTNEJTIyZmFzJTIwZmEtYW5nbGUtcmlnaHQlMjIlM0UlM0MlMkZpJTNFJTNDJTJGYSUzRQ==[\/vc_raw_html]<\/div><\/div><\/div><div class=\"vc_col-sm-6 wpb_column vc_column_container bg-box-trovacasa box3 has_bg_color\"><div class=\"vc_column-inner us_custom_4cfaf1ad\"><div class=\"wpb_wrapper\"><\/div><\/div><\/div><\/div><\/div><\/section><section class=\"l-section wpb_row us_custom_5709a925 row_trovacasa us_animate_this height_large width_full\"><div class=\"l-section-h i-cf\"><div class=\"g-cols vc_row via_flex valign_top type_default stacking_default\"><div class=\"vc_col-sm-6 wpb_column vc_column_container bg-box-trovacasa box3 has_bg_color\"><div class=\"vc_column-inner us_custom_f0d499da\"><div class=\"wpb_wrapper\"><\/div><\/div><\/div><div class=\"vc_col-sm-6 wpb_column vc_column_container center-content-col\"><div class=\"vc_column-inner\"><div class=\"vc_column-overlay\" style=\"background:rgba(255,255,255,0.65)\"><\/div><div class=\"wpb_wrapper\">[vc_custom_heading text=&#8221;DATA SCIENCE FOR HEALTH (DASCH) LAB&#8221; font_container=&#8221;tag:h2|text_align:center&#8221; use_theme_fonts=&#8221;yes&#8221; css=&#8221;%7B%22default%22%3A%7B%22color%22%3A%22%232d70a6%22%7D%7D&#8221;]<div class=\"wpb_text_column\"><div class=\"wpb_wrapper\"><p>The <strong>DaScH-Lab<\/strong> can rely on the expertise of a diverse group of computational and machine-learning scientists working at the interface with experimental teams on a wide range of life science challenges.<\/p>\n<\/div><\/div>[vc_raw_html el_class=&#8221;btn_center_scarica&#8221;]JTNDYSUyMGhyZWYlM0QlMjIlMkZlbiUyRmxhLXJpY2VyY2EtdGxzJTJGZGF0YS1zY2llbmNlLWZvci1oZWFsdGgtZGFzY2gtbGFiJTJGJTIyJTIwY2xhc3MlM0QlMjJzY2FyaWNhX2J0biUyMiUzRVJlYWQlMjBNb3JlJTIwJTNDaSUyMGNsYXNzJTNEJTIyZmFzJTIwZmEtYW5nbGUtcmlnaHQlMjIlM0UlM0MlMkZpJTNFJTNDJTJGYSUzRQ==[\/vc_raw_html]<\/div><\/div><\/div><\/div><\/div><\/section><section class=\"l-section wpb_row us_custom_5709a925 row_trovacasa us_animate_this height_large width_full\"><div class=\"l-section-h i-cf\"><div class=\"g-cols vc_row via_flex valign_top type_default stacking_default\"><div class=\"vc_col-sm-6 wpb_column vc_column_container center-content-col\"><div class=\"vc_column-inner\"><div class=\"vc_column-overlay\" style=\"background:rgba(255,255,255,0.65)\"><\/div><div class=\"wpb_wrapper\">[vc_custom_heading text=&#8221;Hyper Antibody Research Development (HARD) LAB&#8221; font_container=&#8221;tag:h2|text_align:center&#8221; use_theme_fonts=&#8221;yes&#8221; css=&#8221;%7B%22default%22%3A%7B%22color%22%3A%22%232d70a6%22%7D%7D&#8221;]<div class=\"wpb_text_column\"><div class=\"wpb_wrapper\"><p style=\"text-align: center;\"><span lang=\"EN-GB\">The High-Throughput Antibody Research and Development Lab (HARD-Lab) is dedicated to cutting-edge research and development in the field of antibody-based diagnostics and therapeutics, focusing on areas of medical importance such as oncology, metabolic, infectious, and rare diseases.<\/span><\/p>\n<\/div><\/div>[vc_raw_html el_class=&#8221;btn_center_scarica&#8221;]JTNDYSUyMGhyZWYlM0QlMjIlMkZlbiUyRmxhLXJpY2VyY2EtdGxzJTJGaHlwZXItYW50aWJvZHktcmVzZWFyY2gtZGV2ZWxvcG1lbnQtaGFyZC1sYWIlMkYlMjIlMjBjbGFzcyUzRCUyMnNjYXJpY2FfYnRuJTIyJTNFUmVhZCUyMG1vcmUlMjAlM0NpJTIwY2xhc3MlM0QlMjJmYXMlMjBmYS1hbmdsZS1yaWdodCUyMiUzRSUzQyUyRmklM0UlM0MlMkZhJTNF[\/vc_raw_html]<\/div><\/div><\/div><div class=\"vc_col-sm-6 wpb_column vc_column_container bg-box-trovacasa box3 has_bg_color\"><div class=\"vc_column-inner us_custom_33fc64a5\"><div class=\"wpb_wrapper\"><\/div><\/div><\/div><\/div><\/div><\/section><section class=\"l-section wpb_row us_custom_5709a925 row_trovacasa us_animate_this height_large width_full\"><div class=\"l-section-h i-cf\"><div class=\"g-cols vc_row via_flex valign_top type_default stacking_default\"><div class=\"vc_col-sm-6 wpb_column vc_column_container bg-box-trovacasa box3 has_bg_color\"><div class=\"vc_column-inner us_custom_a0a6362f\"><div class=\"wpb_wrapper\"><\/div><\/div><\/div><div class=\"vc_col-sm-6 wpb_column vc_column_container center-content-col\"><div class=\"vc_column-inner\"><div class=\"vc_column-overlay\" style=\"background:rgba(255,255,255,0.65)\"><\/div><div class=\"wpb_wrapper\">[vc_custom_heading text=&#8221;MASS SPECTROMETRY UNIT&#8221; font_container=&#8221;tag:h2|text_align:center&#8221; use_theme_fonts=&#8221;yes&#8221; css=&#8221;%7B%22default%22%3A%7B%22color%22%3A%22%232d70a6%22%7D%7D&#8221;]<div class=\"wpb_text_column\"><div class=\"wpb_wrapper\"><p style=\"text-align: center;\">The <strong>Mass Spectrometry Unit<\/strong> (MSU) is a well-established reality within TLS consisting of a multidisciplinary team which, by combining<strong> mass spectrometry<\/strong> with <strong>bioinformatic data processing<\/strong>, deals with the cross-sectional analysis of a wide variety of samples to investigate their protein and metabolic profile.<\/p>\n<\/div><\/div>[vc_raw_html el_class=&#8221;btn_center_scarica&#8221;]JTNDYSUyMGhyZWYlM0QlMjIlMkZlbiUyRmxhLXJpY2VyY2EtdGxzJTJGbWFzcy1zcGVjdHJvbWV0cnktdW5pdCUyRiUyMiUyMGNsYXNzJTNEJTIyc2NhcmljYV9idG4lMjIlM0VSZWFkJTIwbW9yZSUyMCUzQ2klMjBjbGFzcyUzRCUyMmZhcyUyMGZhLWFuZ2xlLXJpZ2h0JTIyJTNFJTNDJTJGaSUzRSUzQyUyRmElM0U=[\/vc_raw_html]<\/div><\/div><\/div><\/div><\/div><\/section><section class=\"l-section wpb_row us_custom_81af620e row_trovacasa row_trocavasa2 us_animate_this height_large width_full\"><div class=\"l-section-h i-cf\"><div class=\"g-cols vc_row via_flex valign_top type_default reversed stacking_default\"><div class=\"vc_col-sm-6 wpb_column vc_column_container bg-box-trovacasa box2 has_bg_color\"><div class=\"vc_column-inner us_custom_b23de9e7\"><div class=\"wpb_wrapper\"><\/div><\/div><\/div><div class=\"vc_col-sm-6 wpb_column vc_column_container center-content-col\"><div class=\"vc_column-inner\"><div class=\"vc_column-overlay\" style=\"background:rgba(255,255,255,0.65)\"><\/div><div class=\"wpb_wrapper\">[vc_custom_heading text=&#8221;ORPHAN DISEASES&#8221; font_container=&#8221;tag:h2|text_align:center&#8221; use_theme_fonts=&#8221;yes&#8221; css=&#8221;%7B%22default%22%3A%7B%22color%22%3A%22%232d70a6%22%7D%7D&#8221;]<div class=\"wpb_text_column\"><div class=\"wpb_wrapper\"><p><strong>Fondazione Toscana Life Sciences<\/strong> has explicitly identified among its institutional objectives a strategic role in the field of rare diseases, with particular emphasis on acting as a translational bridge between basic research and industrial applications in the biomedical and pharmaceutical sectors<\/p>\n<\/div><\/div>[vc_raw_html el_class=&#8221;btn_center_scarica&#8221;]JTNDYSUyMGhyZWYlM0QlMjIlMkZlbiUyRnRscy1yZXNlYXJjaCUyRm9ycGhhbi1kaXNlYXNlcyUyRiUyMiUyMGNsYXNzJTNEJTIyc2NhcmljYV9idG4lMjIlM0VSZWFkJTIwbW9yZSUyMCUzQ2klMjBjbGFzcyUzRCUyMmZhcyUyMGZhLWFuZ2xlLXJpZ2h0JTIyJTNFJTNDJTJGaSUzRSUzQyUyRmElM0U=[\/vc_raw_html]<\/div><\/div><\/div><\/div><\/div><\/section><section class=\"l-section wpb_row us_custom_81af620e row_trovacasa row_trocavasa2 us_animate_this height_large width_full\"><div class=\"l-section-h i-cf\"><div class=\"g-cols vc_row via_flex valign_top type_default stacking_default\"><div class=\"vc_col-sm-6 wpb_column vc_column_container center-content-col\"><div class=\"vc_column-inner\"><div class=\"vc_column-overlay\" style=\"background:rgba(255,255,255,0.65)\"><\/div><div class=\"wpb_wrapper\">[vc_custom_heading text=&#8221;Molecular Immunology and Translational Oncology (MITO) Lab&#8221; font_container=&#8221;tag:h2|text_align:center&#8221; use_theme_fonts=&#8221;yes&#8221; css=&#8221;%7B%22default%22%3A%7B%22color%22%3A%22%232d70a6%22%7D%7D&#8221;]<div class=\"wpb_text_column\"><div class=\"wpb_wrapper\"><p style=\"text-align: center;\">The <strong>Molecular Immunology and Translational Oncology<\/strong> (MITO) laboratory, led by Dr. Anna Kabanova, was established in 2019 with the support of the Italian Association for Cancer Research (AIRC). The <strong>MITO<\/strong> team investigates B-cell biology in health and disease, leveraging these insights to disrupt metabolic vulnerabilities in leukemia and engineer synthetic cell and antibody-based therapies.<\/p>\n<\/div><\/div>[vc_raw_html el_class=&#8221;btn_center_scarica&#8221;]JTNDYSUyMGhyZWYlM0QlMjIlMkZlbiUyRmxhLXJpY2VyY2EtdGxzJTJGbW9sZWN1bGFyLWltbXVub2xvZ3ktYW5kLXRyYW5zbGF0aW9uYWwtb25jb2xvZ3klMkYlMjIlMjBjbGFzcyUzRCUyMnNjYXJpY2FfYnRuJTIyJTNFUmVhZCUyMG1vcmUlMjAlM0NpJTIwY2xhc3MlM0QlMjJmYXMlMjBmYS1hbmdsZS1yaWdodCUyMiUzRSUzQyUyRmklM0UlM0MlMkZhJTNF[\/vc_raw_html]<\/div><\/div><\/div><div class=\"vc_col-sm-6 wpb_column vc_column_container bg-box-trovacasa box2 has_bg_color\"><div class=\"vc_column-inner us_custom_4adc2b91\"><div class=\"wpb_wrapper\"><\/div><\/div><\/div><\/div><\/div><\/section><section class=\"l-section wpb_row us_custom_636189fa row_scarica_presentazione us_animate_this height_auto with_img\"><div class=\"l-section-img\" data-img-width=\"1244\" data-img-height=\"708\" style=\"background-image: url(https:\/\/www.toscanalifesciences.org\/wp-content\/uploads\/2021\/02\/demo-blue-bg.jpg);\"><\/div><div class=\"l-section-h i-cf\"><div class=\"g-cols vc_row via_flex valign_top type_default stacking_default\"><div class=\"vc_col-sm-12 wpb_column vc_column_container\"><div class=\"vc_column-inner\"><div class=\"wpb_wrapper\">[vc_raw_html]JTVCZ25ld3NsZXR0ZXJ0bHMlNUQlNUIlMkZnbmV3c2xldHRlcnRscyU1RA==[\/vc_raw_html]<\/div><\/div><\/div><\/div><\/div><\/section><section class=\"l-section wpb_row us_custom_f74ef8b2 us_animate_this height_medium\" id=\"mid-sec-title-hanno-scelto\"><div class=\"l-section-h i-cf\"><div class=\"g-cols vc_row via_flex valign_top type_default stacking_default\"><div class=\"vc_col-sm-12 wpb_column vc_column_container\"><div class=\"vc_column-inner\"><div class=\"wpb_wrapper\">[vc_custom_heading text=&#8221;TLS Research&#8221; font_container=&#8221;tag:h2|text_align:center&#8221; use_theme_fonts=&#8221;yes&#8221; css=&#8221;%7B%22default%22%3A%7B%22color%22%3A%22_content_primary%22%2C%22font-weight%22%3A%22400%22%2C%22text-transform%22%3A%22uppercase%22%7D%7D&#8221;][vc_custom_heading text=&#8221;visit the other sections&#8221; font_container=&#8221;tag:h3|text_align:center&#8221; use_theme_fonts=&#8221;yes&#8221; css=&#8221;%7B%22default%22%3A%7B%22color%22%3A%22%23404040%22%2C%22text-align%22%3A%22center%22%7D%7D&#8221;]<\/div><\/div><\/div><\/div><\/div><\/section><section class=\"l-section wpb_row us_custom_5709a925 centering_columns us_animate_this height_auto\"><div class=\"l-section-h i-cf\"><div class=\"g-cols vc_row via_flex valign_top type_default stacking_default\"><div class=\"vc_col-sm-4 wpb_column vc_column_container col_trova_casa\"><div class=\"vc_column-inner us_custom_ec019216 us_animate_this\"><div class=\"vc_column-overlay\" style=\"background:rgba(255,255,255,0.65)\"><\/div><div class=\"wpb_wrapper\"><div class=\"w-image align_none\"><div class=\"w-image-h\"><img loading=\"lazy\" decoding=\"async\" width=\"1613\" height=\"1075\" src=\"https:\/\/www.toscanalifesciences.org\/wp-content\/uploads\/2022\/04\/Le-pubblicazioni-scientifiche_TLS-76.jpg\" class=\"attachment-full size-full\" alt=\"\" srcset=\"https:\/\/www.toscanalifesciences.org\/wp-content\/uploads\/2022\/04\/Le-pubblicazioni-scientifiche_TLS-76.jpg 1613w, https:\/\/www.toscanalifesciences.org\/wp-content\/uploads\/2022\/04\/Le-pubblicazioni-scientifiche_TLS-76-300x200.jpg 300w, https:\/\/www.toscanalifesciences.org\/wp-content\/uploads\/2022\/04\/Le-pubblicazioni-scientifiche_TLS-76-1024x682.jpg 1024w, https:\/\/www.toscanalifesciences.org\/wp-content\/uploads\/2022\/04\/Le-pubblicazioni-scientifiche_TLS-76-600x400.jpg 600w\" sizes=\"(max-width: 1613px) 100vw, 1613px\" \/><\/div><\/div>[vc_custom_heading text=&#8221;Scientific Publications&#8221; font_container=&#8221;tag:h2|text_align:center&#8221; use_theme_fonts=&#8221;yes&#8221; css=&#8221;%7B%22default%22%3A%7B%22color%22%3A%22%232d70a6%22%7D%7D&#8221;]<div class=\"wpb_text_column\"><div class=\"wpb_wrapper\"><p style=\"text-align: center;\">In recent years, the increasing commitment of<strong> TLS<\/strong> to in-house research has produced a significant growth of the <strong>scientific contribution<\/strong> of the foundation\u2019s researchers<\/p>\n<\/div><\/div>[vc_raw_html el_class=&#8221;btn_center_scarica&#8221;]JTNDYSUyMGhyZWYlM0QlMjIlMkZlbiUyRnNjaWVudGlmaWMtcHVibGljYXRpb25zJTJGJTIyJTIwY2xhc3MlM0QlMjJzY2FyaWNhX2J0biUyMiUzRVJlYWQlMjBNb3JlJTIwJTNDaSUyMGNsYXNzJTNEJTIyZmFzJTIwZmEtYW5nbGUtcmlnaHQlMjIlM0UlM0MlMkZpJTNFJTNDJTJGYSUzRQ==[\/vc_raw_html]<\/div><\/div><\/div><\/div><\/div><\/section>\n","protected":false},"excerpt":{"rendered":"[vc_custom_heading text=\"Research Projects\" font_container=\"tag:h2|text_align:center\" use_theme_fonts=\"yes\" css=\"%7B%22default%22%3A%7B%22color%22%3A%22%23015294%22%2C%22font-weight%22%3A%22400%22%2C%22text-transform%22%3A%22uppercase%22%7D%7D\"]TLS is involved in an increasing number of research projects aimed at responding to major...","protected":false},"author":1,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_acf_changed":false,"footnotes":""},"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v23.2 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Research Projects - Toscana Life Sciences<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.toscanalifesciences.org\/en\/research-projects\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Research Projects - Toscana 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