Emanuele Roscioli is a cell and molecular biologist with expertise on the mechanisms underlying cell division and chromosome segregation in mammalian cells. He trained in the laboratory of Dr. Patrizia Lavia at IBPM-CNR c/o Sapienza University of Rome (Italy) where he got his Bachelor degree in Biological Sciences in 2006, his Master degree in Genetics and Molecular Biology in 2007 and his PhD in Genetics and Molecular Biology in 2011.
For his postdoctral training, he moved to the laboratory of Prof. Daniela Cimini at Virginia Tech (USA) where he worked until 2014. Emanuele was part of an interdisciplinary project aimed at investigating the mechanics and dynamics of the mitotic apparatus. For this project, he worked in collaboration with the group of Dr. Iva Tolić (Max Planck Institute-CBG, Dresden, Germany, now at Ruđer Bošković Institute, Zagreb, Croatia) using biophysical approaches to study the mechanichal properties of the kinetochore and the mitotic spindle.
Subsequently, from 2015, Emanuele worked as Research Fellow in the laboratory of Prof. Andrew McAinsh at the University of Warwick (UK) where he contributed to develop a software for the 3D tracking of fluorescently-labelled proteins. For his project, he set-up in vitro and in vivo cell-based assays to map the architecture of the human kinetochore in response to different mechanical inputs.
Throughout his career, Emanuele was part of several interdisciplinary projects collaborating with biochemists, biophysicist and mathematical modellers and gaining expertise in microscopy, image analysis and byophisical techniques.
Since 2020, Emanuele is a Researcher in the group led by Dr. Rino Rappuoli at Toscana Life Sciences Foundation (TLS) where he works on the development of monoclonal antibodies (mAbs) against antimicrobial resistant bacteria and on setting-up functional assays to test their efficacy in human cells.